We present Atacama Large Millimeter/submillimeter Array (ALMA) imaging of molecular gas across the full star-forming disk of the barred spiral galaxy M83 in CO(J = 1-0). We jointly deconvolve the data from ALMA's 12 m, 7 m, and Total Power arrays using the MIRIAD package. The data have a mass sensitivity and resolution of 10(4) M (circle dot) (3 sigma) and 40 pc-sufficient to detect and resolve a typical molecular cloud in the Milky Way with a mass and diameter of 4 x 10(5) M (circle dot) and 40 pc, respectively. The full disk coverage shows that the characteristics of molecular gas change radially from the center to outer disk, with the locally measured brightness temperature, velocity dispersion, and integrated intensity (surface density) decreasing outward. The molecular gas distribution shows coherent large-scale structures in the inner part, including the central concentration, offset ridges along the bar, and prominent molecular spiral arms. However, while the arms are still present in the outer disk, they appear less spatially coherent, and even flocculent. Massive filamentary gas concentrations are abundant even in the interarm regions. Building up these structures in the interarm regions would require a very long time (greater than or similar to 100 Myr). Instead, they must have formed within stellar spiral arms and been released into the interarm regions. For such structures to survive through the dynamical processes, the lifetimes of these structures and their constituent molecules and molecular clouds must be long (greater than or similar to 100 Myr). These interarm structures host little or no star formation traced by H alpha. The new map also shows extended CO emission, which likely represents an ensemble of unresolved molecular clouds.

We present an extensive grid of numerical simulations quantifying the uncertainties in measurements of the tip of the red giant branch (TRGB). These simulations incorporate a luminosity function composed of 2 mag of red giant branch (RGB) stars leading up to the tip, with asymptotic giant branch (AGB) stars contributing exclusively to the luminosity function for at least a magnitude above the RGB tip. We quantify the sensitivity of the TRGB detection and measurement to three important error sources: (1) the sample size of stars near the tip, (2) the photometric measurement uncertainties at the tip, and (3) the degree of self-crowding of the RGB population. The self-crowding creates a population of supra-TRGB stars due to the blending of one or more RGB stars just below the tip. This last population is ultimately difficult, although still possible, to disentangle from true AGB stars. In the analysis given here, the precepts and general methodology as used in the Chicago-Carnegie Hubble Program (CCHP) have been followed. However, in the appendix, we introduce and test a set of new tip detection kernels, which internally incorporate self-consistent smoothing. These are generalizations of the two-step model used by the CCHP (smoothing followed by Sobel-filter tip detection), where the new kernels are based on successive binomial-coefficient approximations to the derivative-of-a-Gaussian edge-detector, as is commonly used in modern digital image processing.

Given the recent successful launch of the James Webb Space Telescope, determining robust calibrations of the slopes and absolute magnitudes of the near- to mid-infrared tip of the red-giant branch (TRGB) will be essential to measuring precise extragalactic distances via this method. Using ground-based data of the Large Magellanic Cloud from the Magellanic Clouds Photometric Survey along with near-infrared (NIR) data from 2MASS and mid-infrared (MIR) data collected as a part of the SAGE survey using the Spitzer Space Telescope, we present slopes and zero-points for the TRGB in the optical (VI), NIR (JHK), and MIR ([3.6] and [4.5]) bandpasses. These calibrations utilize stars +0.3 +/- 0.1 mag below the tip, providing a substantial statistical improvement over previous calibrations which only used the sample of stars narrowly encompassing the tip.

The J-region Asymptotic Giant Branch (JAGB) method is a standard candle that leverages the constant luminosities of color-selected, carbon-rich AGB stars, measured in the near-infrared at 1.2 mu m. The Chicago-Carnegie Hubble Program has obtained JWST imaging of the SN Ia host galaxies NGC 7250, NGC 4536, and NGC 3972. With these observations, the JAGB method can be studied for the first time using JWST. Lee et al. demonstrated the JAGB magnitude is optimally measured in the outer disks of galaxies, because in the inner regions the JAGB magnitude can vary significantly due to a confluence of reddening, blending, and crowding effects. However, determining where the "outer disk" lies can be subjective. Therefore, we introduce a novel method for systematically selecting the outer disk. In a given galaxy, the JAGB magnitude is first separately measured in concentric regions, and the "outer disk" is then defined as the first radial bin where the JAGB magnitude stabilizes to a few hundredths of a magnitude. After successfully employing this method in our JWST galaxy sample, we find the JAGB stars are well segregated from other stellar populations in color-magnitude space, and have observed dispersions about their individual F115W modes of sigma N7250 = 0.32 mag, sigma N4536 = 0.34 mag, and sigma N3972 = 0.35 mag. These measured dispersions are similar to the scatter measured for the JAGB stars in the LMC using 2MASS data (sigma = 0.33 mag). In conclusion, the JAGB stars as observed with JWST clearly demonstrate their considerable power both as high-precision extragalactic distance indicators and as SN Ia supernova calibrators.

One of the most exciting and pressing issues in cosmology today is the discrepancy between some measurements of the local Hubble constant and other values of the expansion rate inferred from the observed temperature and polarization fluctuations in the cosmic microwave background (CMB) radiation. Resolving these differences holds the potential for the discovery of new physics beyond the standard model of cosmology: Lambda Cold Dark Matter (Lambda CDM), a successful model that has been in place for more than 20 years. Given both the fundamental significance of this outstanding discrepancy, and the many-decades-long effort to increase the accuracy of the extragalactic distance scale, it is critical to demonstrate that the local measurements are convincingly free from residual systematic errors. We review the progress over the past quarter century in measurements of the local value of the Hubble constant, and discuss remaining challenges. Particularly exciting are new data from the James Webb Space Telescope (JWST), for which we present an overview of our program and first results. We focus in particular on Cepheids and the Tip of the Red Giant Branch (TRGB) stars, as well as a relatively new method, the JAGB (J-Region Asymptotic Giant Branch) method, all methods that currently exhibit the demonstrably smallest statistical and systematic uncertainties. JWST is delivering high-resolution near-infrared imaging data to both test for and to address directly several of the systematic uncertainties that have historically limited the accuracy of extragalactic distance scale measurements (e.g., the dimming effects of interstellar dust, chemical composition differences in the atmospheres of stars, and the crowding and blending of Cepheids contaminated by nearby previously unresolved stars). For the first galaxy in our program, NGC 7250, the high-resolution JWST images demonstrate that many of the Cepheids observed with the Hubble Space Telescope (HST) are significantly crowded by nearby neighbors. Avoiding the more significantly crowded variables, the scatter in the JWST near-infrared (NIR) Cepheid PL relation is decreased by a factor of two compared to those from HST, illustrating the power of JWST for improvements to local measurements of H0. Ultimately, these data will either confirm the standard model, or provide robust evidence for the inclusion of additional new physics.

Using an updated and significantly augmented sample of Cepheid and tip of the red giant branch (TRGB) distances to 28 nearby spiral and irregular galaxies, covering a wide range of metallicities, we have searched for evidence of a correlation of the zero-point of the Cepheid period-luminosity relation with H ii region (gas-phase) metallicities. Our analysis, for the 21 galaxies closer than 12.5 Mpc, results in the following conclusions: (1) The zero-points of the Cepheid and TRGB distance scales are in remarkably good agreement, with the mean offset in the zero-points of the most nearby distance-selected sample being close to zero, Delta mu o (Cepheid-TRGB) = -0.026 +/- 0.015 mag (for an I-band TRGB zero-point of M I = -4.05 mag); however, for the more distant sample, there is a larger offset between the two distance scales, amounting to -0.073 +/- 0.057 mag Delta mu o (Cepheids-TRGB) = -0.026 +/- 0.015 mag, for an I-band TRGB zero-point of M I = -4.05 mag. (2) The individual differences, about that mean, have a measured scatter of +/- 0.068 mag. (3) We find no statistically significant evidence for a metallicity dependence in the Cepheid distance scale using the reddening-free W(V, VI) period-luminosity relation: Delta mu o (Cepheid - TRGB) = - 0.022( +/- 0.015) x ([O/H] - 8.50) - 0.003(+/- 0.007).

We introduce the NASA/IPAC Extragalactic Database (NED) Local Volume Sample (NED-LVS), a subset of similar to 1.9 million objects with distances out to 1000Mpc. We use UV and IR fluxes available in NED from all-sky surveys to derive physical properties, and estimate the completeness relative to the expected local luminosity density. The completeness relative to near-IR luminosities (which traces a galaxy's stellar mass) is roughly 100% at D< 30 Mpc and remains moderate (70%) out to 300 Mpc. For brighter galaxies (greater than or similar to L-*), NED-LVS is similar to 100% complete out to similar to 400Mpc. When compared to other local Universe samples (GLADE and HECATE), all three are similar to 100% complete below 30Mpc. At distances beyond similar to 80 Mpc, NED-LVS is more complete than both GLADE and HECATE by similar to 10%-20%. NED-LVS is the underlying sample for the NED gravitational-wave follow-up service (NED-GWF), which provides prioritized lists of host candidates for GWevents within minutes of alerts issued by the LIGO-Virgo-KAGRA collaboration. We test the prioritization of galaxies in the volume of GW170817 by three physical properties, where we find that both stellar mass and inverse specific star formation rate place the correct host galaxy in the top 10. In addition, NED-LVS can be used for a wide variety of other astrophysical studies: galaxy evolution, star formation, large-scale structure, galaxy environments, and more. The data in NED are updated regularly, and NED-LVS will be updated concurrently. Consequently, NED-LVS will continue to provide an increasingly complete sample of galaxies for a multitude of astrophysical research areas for years to come.

Star-forming galaxies can exhibit strong morphological differences between the rest-frame far-UV and optical, reflecting inhomogeneities in star formation and dust attenuation. We exploit deep, high-resolution, NIRCAM seven-band observations to take a first look at the morphology of galaxies in the epoch of reionization (z > 7), and its variation in the rest-frame wavelength range between Ly alpha and 6000-4000 angstrom, at z = 7-12. We find no dramatic variations in morphology with wavelength-of the kind that would have overturned anything we have learned from the Hubble Space Telescope. No significant trends between morphology and wavelengths are detected using standard quantitative morphology statistics. We detect signatures of mergers/interactions in 4/19 galaxies. Our results are consistent with a scenario in which Lyman-break galaxies-observed when the universe is only 400-800 Myr old-are growing via a combination of rapid, galaxy-scale star formation supplemented by the accretion of star-forming clumps and interactions.

We exploit James Webb Space Telescope (JWST) NIRCam observations from the GLASS-JWST-Early Release Science program to investigate galaxy stellar masses at z > 7. We first show that JWST observations reduce the uncertainties on the stellar mass by a factor of at least 5-10, when compared with the highest-quality data sets available to date. We then study the UV mass-to-light ratio, finding that galaxies exhibit a a two orders of magnitude range of M/L (UV) values for a given luminosity, indicative of a broad variety of physical conditions and star formation histories. As a consequence, previous estimates of the cosmic stellar-mass density-based on an average correlation between UV luminosity and stellar mass-can be biased by as much as a factor of similar to 6. Our first exploration demonstrates that JWST represents a new era in our understanding of stellar masses at z > 7 and, therefore, of the growth of galaxies prior to cosmic reionization.

The Near Infrared Camera for the James Webb Space Telescope (JWST) is delivering the imagery that astronomers have hoped for ever since JWST was proposed back in the 1990s. In the Commissioning Period that extended from right after launch to early 2022 July, NIRCam has been subjected to a number of performance tests and operational checks. The camera is exceeding prelaunch expectations in virtually all areas, with very few surprises discovered in flight. NIRCam also delivered the imagery needed by the Wavefront Sensing Team for use in aligning the telescope mirror segments.