Zhiyong Wang was appointed acting director of Department of Plant Biology in 2018.

Wang’s research aims to understand how plant growth is controlled by environmental and endogenous signals. Being sessile, plants respond environmental changes by altering their growth behavior. As such, plants display high developmental plasticity and their growth is highly sensitive to environmental conditions. Plants have evolved many hormones that function as growth regulators, and growth is also responsive to the availability of nutrients and energy (photosynthates).

To understand how plant cells perceive and transduce various regulatory signals, and how combinations of complex information are processed into growth decisions, such as shoot cell elongation and root growth, by the cellular circuitry, the Wang lab uses a wide range of cutting-edge technologies in proteomics and genomics, as well as traditional genetic and molecular approaches, and both model systems and crops.

The Wang lab has spent years dissecting the signaling pathway of one major class of plant hormones, brassinosteroids, making it one of the best-studied signal transduction pathways in plants. Brassinosteroids play important roles in a wide array of functions, including cell elongation, photomorphogenesis, and reproductive development, with major effects on plant size and biomass accumulation. Brassinosteroids also have impacts on the response to environmental stresses and resistance to pathogens.

In recent years, research by the Wang lab has uncovered a central growth-regulation network that integrates all major signals that control shoot cell elongation, including brassinosteroids, auxin, gibberellin, light, temperature, the circadian clock, sugar, and pathogen signals. Wang believes that this central growth network will be a major target for genetically engineering high-yield crops.

A major current effort of Wang lab is to map the protein networks using proteomic approaches. Both protein-protein interactions and posttranslational modifications are studies at large scale using mass spectrometry in combination with affinity enrichment, proximity labelling, crosslinking, and synthetic protein interactions. The aim is to establish complete protein and gene networks and to engineer the networks to achieve improved traits.

Wang received his B.S. in plant physiology from Lanzhou University, China, his M.S. from the Institute of Botany, Chinese Academy of Sciences, and his Ph. D. in molecular, cell and developmental biology at UCLA. For more see http://dpb.carnegiescience.edu/labs/wang-lab

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Artwork is courtesy of Mark Belan | artscistudios.com.
September 22, 2022

Palo Alto, CA—Climate change and habitat destruction may have already caused the loss of more than one-tenth of the world’s terrestrial genetic diversity, according to new research led by Carnegie’s Moises Exposito-Alonso and published in Science. This means that it may already be too late to meet the United Nations’ proposed target, announced last year, of protecting 90 percent of genetic diversity for every species by 2030, and that we have to act fast to prevent further losses.

Several hundred species of animals and plants have gone extinct in the industrialized age and human activity has impacted or shrunk half of Earth’s ecosystems, affecting

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August 23, 2022

Palo Alto, CA— Water is inextricably linked to our understanding of life—it makes up most of our planet’s surface and organisms across the tree of life depend on it to function. Yet the ability to survive extremely dry conditions for long periods is crucial to the life cycles of many species—including in plants, which can reproduce from desiccated pollen grains and grow from dried-out seeds.

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Stephanie Hampton
August 12, 2022

Washington, DC— Aquatic ecologist Stephanie Hampton joined Carnegie as Deputy Director of Carnegie’s newly launched Division of Biosphere Sciences and Engineering at the end of July. She arrived from the National Science Foundation, where she was the director of the Division of Environmental Biology. She was also a professor and the former director of an interdisciplinary environmental research center at Washington State University.

“Stephanie’s experience leading the primary funder of basic ecological and evolutionary research in the U.S. has given her a 10-thousand-foot view of the field, which will help us as we implement a new, cross-disciplinary vision

Illustration of a plant growing on a computer chip purchased from Shutterstock.
June 13, 2022

Palo Alto, CA— New work led by Carnegie’s Zhiyong Wang untangles a complex cellular signaling process that’s underpins plants’ ability to balance expending energy on growth and defending themselves from pathogens. These findings, published in Nature Plants, show how plants use complex cellular circuits to process information and respond to threats and environmental conditions.  

“Plants don’t have brains like us, and they may be fixed in place and unable to flee from predators or pathogens, but don’t feel sorry for them, because they’ve evolved an incredible network of information-processing circuits that enable them to ‘

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Revolutionary progress in understanding plant biology is being driven through advances in DNA sequencing technology. Carnegie plant scientists have played a key role in the sequencing and genome annotation efforts of the model plant Arabidopsis thaliana and the soil alga Chlamydomonas reinhardtii. Now that many genomes from algae to mosses and trees are publicly available, this information can be mined using bioinformatics to build models to understand gene function and ultimately for designing plants for a wide spectrum of applications.

 Carnegie researchers have pioneered a genome-wide gene association network Aranet that can assign functions

Ana Bonaca is Staff Member at Carnegie Observatories. Her specialty is stellar dynamics and her research aims to uncover the structure and evolution of our galaxy, the Milky Way, especially the dark matter halo that surrounds it. In her research, she uses space- and ground-based telescopes to measure the motions of stars, and constructs numerical experiments to discover how dark matter affected them.

She arrived in September 2021 from Harvard University where she held a prestigious Institute for Theory and Computation Fellowship. 

Bonaca studies how the uneven pull of our galaxy’s gravity affects objects called globular clusters—spheres made up of a million

Peter Gao's research interests include planetary atmospheres; exoplanet characterization; planet formation and evolution; atmosphere-surface-interior interactions; astrobiology; habitability; biosignatures; numerical modeling.

His arrival in September 2021 continued Carnegie's longstanding tradition excellence in exoplanet discovery and research, which is crucial as the field prepares for an onslaught of new data about exoplanetary atmospheres when the next generation of telescopes come online.

Gao has been a part of several exploratory teams that investigated sulfuric acid clouds on Venus, methane on Mars, and the atmospheric hazes of Pluto. He also

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She joined Carnegie in July 2021 from U.C. San Diego’s Scripps Institution of Oceanography, where she investigated the evolution and structure of planetary interiors, including our own Earth and its Moon, as well as Mars, Mercury, and the moon Ganymede.

Pommier’s experimental petrology and mineral physics work are an excellent addition to Carnegie’s longstanding leadership in lab-based mimicry of the

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