The Zheng Lab uses a wide range of tools and systems in their work, including genetics in model organisms, model organism development, cell culture, biochemistry, proteomics, and genomics. In recent years, their findings have broadened their research scope to include three research areas: 1) The mechanism of cell division. 2) The mechanism of genome organization in development, homeostasis, and aging. 3) The mechanism of endosymbiosis in cnidaria.