Celebrating the Life and Legacy of Maxine Singer
Join us in honoring Maxine Singer, President Emerita of Carnegie Science, whose pioneering research and advocacy transformed the scientific community.
For Memorial Event Attendees
Maxine F. Singer Memorial Symposium
Saturday, December 14, 2024
9:30AM - 4:30PM ET
AAAS Auditorium, Washington, DC
9:30 a.m. Doors Open— Coffee & Tea
10:00 a.m. Welcome and Introductions – John Mulchaey, Interim President Carnegie Science
Morning Session 1: Ethics / Policy – John Mulchaey, Interim President Carnegie Science
- Tribute: David Baltimore, Caltech
- TBD
- Marcia McNutt, President, National Academy of Sciences
Morning Session 2: Biology / Genetics
- Tribute: Harold Varmus, Weill Cornell Medical College
- Mary-Claire King, University of Washington
- Jason Crawford, Yale University
12:45 pm - Lunch Break
Afternoon Session 1: Education / Engaging Society in Science
- Tribute: Derrick Simmons, Math for America DC Alum
- David Spergel, President, Simons Foundation
- Amy Vollmer, Professor Emerita of Biology at Swarthmore College
Afternoon Session 2: Research at Carnegie Science
- Tribute: Wendy Freedman, U Chicago
- Lorenzo Rosa, Biosphere Sciences and Engineering
- Alycia Weinberger, Earth and Planets Laboratory
4:15 p.m. Closing Remarks– John Mulchaey, Interim President Carnegie Science
4:30 p.m.: End
Carnegie Science's First Female President
During her fourteen years as President of Carnegie Science, Maxine Frank Singer led the institution into a new era of discovery and impact. As the first woman in the role, she oversaw the construction of the Magellan telescopes at the Las Campanas Observatory in Chile, which have fueled groundbreaking astrophysics research for over 20 years. She also established Carnegie’s first new research department in over 80 years—the Department of Global Ecology—leading the way in studying large-scale environmental challenges.
Singer prioritized education and outreach, creating programs such as the Capital Science Evening lecture series and the Carnegie Academy for Science Education. Her vision and leadership not only strengthened Carnegie Science’s research capacities but also expanded its role as a vital institution for both scientific discovery and education.
Leading the Way in Genetic Research
After earning her Ph.D. from Yale, Maxine Singer joined the National Institutes of Health (NIH) in 1956—a mere three years after the discovery of the DNA double helix.
Her early research, which focused on RNA and DNA synthesis, helped lay the foundation for the decoding of the genetic code in the 1960s. One of her most significant scientific contributions was the discovery of the LINE-1 DNA sequence, which can "jump" within the human genome, causing mutations that may lead to genetic diseases. This breakthrough reshaped our understanding of genetic mobility and its role in evolution and disease. Singer’s scientific work contributed to the development of molecular biology as we know it today, and her legacy continues to influence generations of researchers.
Advocacy for Ethics in Genetics
Maxine Singer was a key figure in creating ethical guidelines for genetic research during a time when public concern was growing. In the early 1970s, as recombinant DNA research and gene splicing gained public attention, Singer became a trusted voice for balancing scientific progress with public safety. Seeing the potential risks of unregulated genetic research, she urged caution in a co-authored letter in Science which ultimately led to 1975 Asilomar Conference. As an organizer of this historic gathering, Singer helped guide discussions among the 150 scientists in attendance, leading to the adoption of voluntary guidelines and safeguards for high-risk experiments.
Beyond the lab, she was a dedicated advocate for responsible genetic research. Singer engaged with the public at forums, debated critics, and testified before Congress (pictured), helping to build trust and set lasting standards for scientific responsibility. This experience also strengthened her commitment to science education, which she saw as essential for an informed and engaged society.
Science to the People
Throughout her career, Maxine Singer was a dedicated advocate for women and minorities in science. As President of Carnegie Science, she launched several educational outreach initiatives aimed at providing hands-on science experiences to students and teachers in Washington, D.C. Notably, she founded the First Light Saturday science school and the Carnegie Academy for Science Education (CASE), which have served thousands of D.C. students and teachers.
Singer continued to work with CASE and other programs, such as Math for America, long after her retirement. Her advocacy work has left a lasting impact on STEM education and inspired future generations of scientists, educators, and policymakers.
Highlighted Works
Blossoms And the Genes that Make Themby Maxine Singer | June 5, 2018 |
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Exploring Genetic Mechanismsby Maxine Singer and Paul Berg | May 7, 1997 |
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Why Aren't Black Holes Black?by Robert M. Hazen and Maxine Singer | Apr 14, 1997 |
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Dealing With Genes: The Language of Heredityby Paul Berg and Maxine Singer | Jan 1, 1992 |
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Genes and Genomes: A Changing Perspectiveby Maxine Singer and Paul Berg | Feb 28, 1991 |
Genetics and the Law: A Scientist’s View
Yale Law & Policy Review, 1985
Heroines and Role Models
Science, 1991
Thoughts of a Nonmillenarian
Bulletin of the American Academy of Arts and Sciences, 1997
Inspired Choices
Science, 1998
Regulating Human Cloning
Science, 1998
Believing Is Not Understanding
The Washington Post, 1999
Enhancing the Postdoctoral Experience
Issues in Science and Technology, 2000
Shaping the Future for Women in Science
The American Society for Cell Biology Newsletter, 2000
Maxine Singer Speech Repository
Maxine Singer authored 131 papers, including articles, review articles, meeting abstracts, notes, editorial material, and letters. As of November 2024, these papers have been cited 6,487 times.
Top Cited Works:
Highly Repeated Sequences in Mammalian Genomes - 1982
SINEs and LINEs: Highly repeated short and long interspersed sequences in mammalian genomes - 1982
Unit-length line-1 transcripts in human teratocarcinoma cells - 1988
Cytoplasmic ribonucleoprotein complexes containing human LINE-1 protein and RNA - 1996
Summary statement of the Asilomar conference on recombinant DNA molecules - 1975
- 1978: Elected Fellow of the American Academy of Arts and Sciences
- 1988-2002: President of the Carnegie Institution of Washington
- 1990: Elected to the American Philosophical Society
- 1992: Awarded the National Medal of Science for outstanding scientific accomplishments and her commitment to societal responsibility in science
- 1999: First woman to receive the Vannevar Bush Award
- 2007: Awarded the Public Welfare Medal from the National Academy of Sciences
Shared Memories
I met Maxine as a postdoc in Marnie Halpern's lab (then at Carnegie Embryology). It was Maxine's passion for making a difference in the science education of K-12 students that impressed me. So much so that when I was an Assistant Professor, I started BioEYES, a program that uses zebrafish to excite kids about science. When we launched BioEYE in 2002, I asked Maxine to advise our program. Maxine generously shared her wisdom, which is certainly one factor that helped us grow to a program that is all over the world and approaching 200,000 children served.
Maxine told me the following with regard to the state of science education in the US: Image when students were in primary grades, they learned the names of famous baseball players. Then, as they got older, they memorized the rules. In high school, they got to hold a ball and glove or maybe walk on the field. Never did they ever get a chance to play the game. She believed it was essential that every child have a chance to have a hands-on science experience.
Maxine Singer was Carnegie's president when I came to DTM (Department of Terrestrial Magnetism*) as a postdoc and remained so until several years after I was hired onto the scientific staff. She was an absolutely amazing scientist, administrator, and human being.
Despite being my boss's boss and in an utterly different field from me, she was always eager to talk science with me and listen to my ideas about, well, anything. I was lucky enough to live in the same neighborhood as her, so even long after she retired, I would regularly run into her on walks or at the grocery store, and she always wanted to catch up.
She is sorely missed.
*The Department of Terrestrial Magnetism merged with the Geophysical Laboratory to form the Earth and Planets Laboratory in 2020.
I worked with Maxine on the Math for America DC program. She continually pushed to improve the math teaching in DC. Dozens of teachers went through the program, and thousands of students benefitted from their dedicated work in the schools. None of this would have happened without Maxine’s leadership.
Forever grateful to Dr. Maxine Singer🇺🇸 who spearheaded the construction of the twin Magellan telescopes at the Carnegie Las Campanas Observatory in #Chile 🇨🇱that have enabled two decades of breakthrough #astrophysics & #astronomic research.@LCOAstro @sochias_cl @womeninstem https://t.co/CtdfRFNfpS
— Belen Sapag M. (@BSapag) July 25, 2024
Obituary: Maxine Singer (1931-2024) biologist who shaped genetic engineering and fought discrimination https://t.co/zGjyNygXkC
— nature (@Nature) August 3, 2024
Our Office was saddened to hear of the recent passing of Dr. Maxine Singer. Alongside Dr. Marshall Nirenberg, Singer was a key player in deciphering the genetic code. She further supported the field by developing guidelines for safe, ethical genetic research with @theNCI. pic.twitter.com/TeVAvakIc6
— NIH History Office (@historyatnih) July 18, 2024
We lost a great leader today - Maxine Singer, advocate for STEM education for all, besides being a pioneering scientist. Be inspired by her 2010 @SocDevBio Viktor Hamburger Outstanding Educator Prize lecture: https://t.co/oJQj2tMBup. https://t.co/XpSbgGBOMR
— Ida Chow (@clawedfeet) July 10, 2024
Maxine was a giant intellect, scientist & humanist. She was President when I was a Staff Associate @CarnegieDevBio
— A. Sánchez Alvarado (@Planaria1) August 4, 2024
On the occasions we spoke, I always left the room w/ renewed enthusiasm for science & a keener appreciation of the importance & relevance of our work as scientists https://t.co/iBVauoUGQV
Today, we honor the legacy of Maxine Singer, a distinguished biologist and passionate advocate for STEM inclusion, who recently passed away at the age of 93. Singer’s remarkable career embodied a unique blend of scientific excellence and public advocacy. https://t.co/csVv3EL8qK
— Girls Who Code (@GirlsWhoCode) July 18, 2024
Obituaries
The US molecular biologist Maxine Singer made discoveries about the role of enzymes in assembling genetic material.
A leading biochemist, she helped shape guidelines in the 1970s for genetic-engineering while calming public fears of a spread of deadly lab-made microbes.
In the early 1970s, the molecular biologist led seminal discussions on the ethics and risks of genetic experimentation.
In her more than 40-year formal association with NIH, Singer made a lasting impact in nearly every area of the agency’s conduct of fundamental research as well as its administration and scientific workforce recruitment.