When the Gut Gets Tough, the Enterocytes Get Going

Chen, Grischa Y.; Ayres, Janelle S.
2018
IMMUNITY
DOI
10.1016/j.immuni.2018.04.036
It is assumed that collateral damage from the immune system drives intestinal epithelial cell (IEC) expulsion during enteric infections. In this issue of Immunity, Zhai et al. (2018) describe how Drosophila's canonical immune deficiency (Imd) pathway programs IEC delamination in the gut.