Crystal chemical algorithms were used to estimate the chemical composition of selected mineral phases observed with the CheMin X-ray diffractometer onboard the NASA Curiosity rover in Gale crater, Mars. The sampled materials include two wind-blown soils, Rocknest and Gobabeb, six mudstones in the Yellowknife Bay formation (John Klein and Cumberland) and the Murray formation (Confidence Hills, Mojave2, and Telegraph Peak), as well as five sandstones, Windjana and the samples of the unaltered Stimson formation (Big Sky and Okoruso) and the altered Stimson formation (Greenhorn and Lubango). The major mineral phases observed with the CheMin instrument in the Gale crater include plagioclase, sanidine,P2(1)/c and C2/c clinopyroxene, orthopyroxene, olivine, spine], and alunite-jarosite group minerals. The plagioclase analyzed with CheMin has an overall estimated average of An(40(11)) with a range of An(30(2)) to An(63(6)). The soil samples, Rocknest and Gobabeb, have an average of An(56(8)) while the Murray, Yellowknife Bay, unaltered Stimson, and altered Stimson formations have averages of An(38(2)), An(37(5)), An(45(7)), and An(35(6)), respectively. Alkali feldspar, specifically sanidine, average composition is Or(74(17)) with fully disordered Al/Si. Sanidine is most abundant in the Windjana sample (similar to 26 wt% of the crystalline material) and is fully disordered with a composition of Or(87(5)). The P2(1)/c clinopyroxene pigeonite observed in Gale crater has a broad compositional range {[Mg0.95(2)-1.54(17)Fe0.18(17)-1.03(9)Ca0.00-0.28(6)](Sigma 2)Si2O6} with an overall average of Mg1.18(19)Fe0.72(7)Ca0.10(9)Si2O6. The soils have the lowest Mg and highest Fe compositions [Mg0.95(5)Fe1.02(7)Ca0.03(4)Si2O6] of all of the Gale samples. Of the remaining samples, those of the Stimson formation exhibit the highest Mg and lowest Fe [average = Mg1.45(7)Fe0.35(13)Ca0.19(6)Si2O6]. Augite, C2/c clinopyroxene, is detected in just three samples, the soil samples [average = Mg0.92(5)Ca0.72(2)Fe0.36(5)Si2O6] and Windjana (Mg1.03(7)Ca0.75(4)Fe0.21(9)Si2O6).