grenepipe: A flexible, scalable, and reproducible pipeline to automate variant calling from sequence reads.

SUMMARY: We developed grenepipe, an all-in-one Snakemake workflow to streamline the data processing from raw high-throughput sequencing data of individuals or populations to genotype variant calls. Our pipeline offers a range of popular software tools within a single configuration file, automatically installs software dependencies, is highly optimized for scalability in cluster environments, and runs with a single command.