Recent work in my laboratory has demonstrated that, during the first few days of embryogenesis in Arabidopsis thaliana, the maternal allele of many genes plays a functionally more important role than the paternal allele. We have also shown that previous disagreements in the literature regarding the timing of zygotic genome activation were most likely due to effects of hybridization on transcription, that vary between different hybrid combinations of inbred lines. In my seminar, I will present recent and ongoing work to understand more about the genetic and epigenetic basis of post-fertilization transcriptional activation in both isogenic and hybrid embryos of Arabidopsis.