Stanford, CA— Coral reefs are tremendously important for ocean biodiversity, as well as for the economic and aesthetic value they provide to their surrounding communities. Unfortunately they have...
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Washington, D.C. --The Arabidopsis Information Resource (TAIR), a database of genetic and molecular biology data for the laboratory plant Arabidopsis thaliana, is one of the most widely used plant...
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Stanford, CA—Transport proteins are responsible for moving materials such as nutrients and metabolic products through a cell’s outer membrane, which seals and protects all living cells, to the cell’s...
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Stanford, CA—Cereals are grasses that produce grains, the bulk of our food supply. Carnegie’s Plant Biology Department is releasing genome-wide metabolic complements of several cereals including rice...
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Stanford, CA— An international team of 12 leading plant biologists, including Carnegie’s Wolf Frommer, say their discoveries could have profound implications for increasing the supply of food and...
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Valdivia, Chile, and Washington, D.C.—Cancer cells break down sugars and produce the metabolic acid lactate at a much higher rate than normal cells. This phenomenon provides a telltale sign that...
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Washington, D.C. —Until now it has not been clear how salt, a scourge to agriculture, halts the growth of the plant-root system. A team of researchers, led by the Carnegie Institution’s...
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Stanford, CA — Plants grow upward from a tip of undifferentiated tissue called the shoot apical meristem. As the tip extends, stem cells at the center of the meristem divide and increase in numbers....
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Carnegie will receive Phase II funding through Grand Challenges Explorations, an initiative created by the Bill & Melinda Gates Foundation that enables individuals worldwide to test bold ideas to address persistent health and development challenges. Department of Plant Biology Director Wolf...
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Revolutionary progress in understanding plant biology is being driven through advances in DNA sequencing technology. Carnegie plant scientists have played a key role in the sequencing and genome annotation efforts of the model plant Arabidopsis thaliana and the soil alga Chlamydomonas reinhardtii....
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Fresh water constitutes less than 1% of the surface water on earth, yet the importance of this simple molecule to all life forms is immeasurable. Water represents the most vital reagent for chemical reactions occurring in a cell. In plants, water provides the structural support necessary for plant...
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Plants are not as static as you think. David Ehrhardt combines confocal microscopy with novel visualization methods to see the three-dimensional movement  within live plant cells to reveal the other-worldly cell choreography that makes up plant tissues. These methods allow his group to explore cell...
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Steroids are important hormones in both animals and plants. They bulk up plants just as they do human athletes, but the pathway of molecular signals that tell the genes to boost growth and development is more complex in plant cells than in animal cells. Unlike animals, plants do not have glands to...
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Arthur Grossman believes that the future of plant science depends on research that spans ecology, physiology, molecular biology and genomics. As such, work in his lab has been extremely diverse. He identifies new functions associated with photosynthetic processes, the mechanisms of coral bleaching...
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Stanford, CA— Algae may hold the key to feeding the world’s burgeoning population. Don’t worry; no one is going to make you eat them. But because they are more efficient than most plants at taking in...
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Stanford, CA— With a growing world population and a changing climate, understanding how agriculturally important plants respond to drought is crucial. New work from a team led by Carnegie’s José...
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Stanford, CA— Proteins are the machinery that accomplishes almost every task in every cell in every living organism. The instructions for how to build each protein are written into a cell’s DNA. But...
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January 30, 2017

Stanford, CA—New work from Carnegie’s Shouling Xu and Zhiyong Wang reveals that the process of synthesizing many important master proteins in plants involves extensive modification, or “tagging” by sugars after the protein is assembled. Their work uncovers both similarity and distinction between plants and animals in their use of this protein modification. It is published by Proceedings of the National Academy of Sciences.

The blueprint for making all proteins is encoded in DNA. The genetic code tells the cellular protein-making apparatus the correct order in which to string together the amino acids that are the building blocks of every protein. Often, after their DNA code has

Carnegie Science, Carnegie Institution, Carnegie Institution for Science
December 14, 2016

Stanford, CA—Climate change and recent heat waves have put agricultural crops at risk, which means that understanding how plants respond to elevated temperatures is crucial for protecting our environment and food supply.

For many plants, even a small increase in average temperature can profoundly affect their growth and development. In the often-studied mustard plant called Arabidopsis, elevated temperatures cause the plants to grow longer stems and thinner leaves in order to cope with the heat stress.

New work led by Carnegie’s Zhiyong Wang uncovers the system by which plants regulate their response to heat differently between daytime and nighttime. It is published by

October 11, 2016

Stanford, CA—We generally think of inheritance as the genetic transfer from parent to offspring and that evolution moves toward greater complexity. But there are other ways that genes are transferred between organisms.

Sometimes a “host” organism can obtain genes from another organism that resides within its own cell (called an endosymbiont) through a process known as endosymbiotic gene transfer. At other times, an organism can obtain genes from a creature that lives in the surrounding environment, or from something that it eats, which is called horizontal gene transfer.

Furthermore, some levels of gene transfer can result in extensive loss of genes and genome reduction,

October 4, 2016

Stanford, CA— A feature thought to make plants sensitive to drought could actually hold the key to them coping with it better, according to new findings published by eLife, from Kathryn Barton of the Carnegie Institution for Science (Department of Plant Biology).

 Plants that are resistant to the hormone abscisic acid (ABA) have until now been understood to be bad at coping with drought. However, Barton and her team have now discovered ABA-resistant varieties that grow better than their normal neighbors when water is scarce. The new research suggests breeders should explore them for “stay green” traits.

 “When breeders are looking for plants able to withstand drought, they

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Revolutionary progress in understanding plant biology is being driven through advances in DNA sequencing technology. Carnegie plant scientists have played a key role in the sequencing and genome annotation efforts of the model plant Arabidopsis thaliana and the soil alga Chlamydomonas reinhardtii. Now that many genomes from algae to mosses and trees are publicly available, this information can be mined using bioinformatics to build models to understand gene function and ultimately for designing plants for a wide spectrum of applications.

 Carnegie researchers have pioneered a genome-wide gene association network Aranet that can assign functions to genes for which no function had

Carnegie researchers recently constructed genetically encoded FRET sensors for a variety of important molecules such as glucose and glutamate. The centerpiece of these sensors is a recognition element derived from the superfamily of bacterial binding protiens called periplasmic binding protein (PBPs), proteins that are primary receptors for moving chemicals  for hundreds of different small molecules. PBPs are ideally suited for sensor construction. The scientists fusie individual PBPs with a pair of variants and produced a large set of sensors, e.g. for sugars like maltose, ribose and glucose or for the neurotransmitter glutamate. These sensors have been adopted for measurement of sugar

Today, humanity is increasingly aware of the impact it has on the environment and the difficulties caused when the environment impacts our communities. Environmental change can be particularly harsh when the plants we use for food, fuel, feed and fiber are affected by this change. High salinity is an agricultural contaminant of increasing significance. Not only does this limit the land available for use in agriculture, but in land that has been used for generations, the combination of irrigation and evaporation gradually leads to increasing soil salinity.

The Dinneny lab focuses on understanding how developmental processes such as cell-type specification regulate responses to

Carnegie will receive Phase II funding through Grand Challenges Explorations, an initiative created by the Bill & Melinda Gates Foundation that enables individuals worldwide to test bold ideas to address persistent health and development challenges. Department of Plant Biology Director Wolf Frommer,  with a team of researchers from the International Rice Research Institute, Kansas State University, and Iowa State University, will continue to pursue an innovative global health research project, titled “Transformative Strategy for Controlling Rice Blight.”

Rice bacterial blight is one of the major challenges to food security, and this project aims to achieve broad, durable

It’s common knowledge that light is essential for plants to perform photosynthesis—converting light energy into chemical energy by transforming carbon dioxide and water into sugars for fuel. Plants maximize the process by bending toward the light in a process called phototropism, which is particularly important for germinated seedlings to maximize light capture for growth. Winslow Briggs has been a worldwide leader in unraveling the molecular mechanisms behind this essential plant process.

Over a decade ago Briggs and colleagues discovered and first characterized the photoreceptor family that mediates this directional response and named the two members phototropin 1 and

Plants are not as static as you think. David Ehrhardt combines confocal microscopy with novel visualization methods to see the three-dimensional movement  within live plant cells to reveal the other-worldly cell choreography that makes up plant tissues. These methods allow his group to explore cell-signaling and cell-organizational events as they unfold.

These methods allow his lab to investigate plant cell development and structure and molecular genetics to understand the organization and dynamic behaviors of molecules and organelles. The group tackles how cells generate asymmetries and specific shapes. A current focus is how the cortical microtubule cytoskeleton— an interior

Young investigator Martin Jonikas has broad ambitions: to transform our fundamental understanding of photosynthetic organisms by developing game-changing tools. In the long run, his lab aims to increase photosynthetic efficiency of crops, which could improve food production around the world.

When photosynthesis first evolved, the atmosphere contained much more carbon dioxide and much less oxygen than it does today. As a result, the photosynthetic machinery of many organisms may not be completely optimized for today’s environment.

The protein responsible for fixing carbon dioxide—called Rubisco—worked very well in the Earth’s early atmosphere. As photosynthetic organisms

One way to adapt to climate change is to understand how plants can thrive in the changing environment. José Dinneny looks at the mechanisms that control environmental responses in plants, including responses to salty soils and different moisture conditions—work that provides the foundation for developing crops for the changing climate.

The Dinneny  lab focuses on understanding how developmental processes such as cell-type specification regulate responses to environmental change. Most studies have considered the organ or even the whole organism as a single responsive unit and ignore the potential diversity of responses by the various cell-types composing an organism. Dinneny has