AudioStanford, CA—Sugars are an essential source of energy for microrganisms, animals, and humans. They are produced by plants, which convert...
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New work has for the first time elucidated the atomic structures of the bacterial prototype of sugar transporters, termed “SWEET” transporters, found in plants and humans. These bacterial sugar...
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AudioStanford, CA—Everyone’s heard of the birds and the bees. But that old expression leaves out the flowers that are being fertilized. The...
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AudioStanford, CA—Soil is a microscopic maze of nooks and crannies that hosts a wide array of life. Plants explore this environment by...
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AudioStanford, CA— A team of researchers studying a flowering plant has zeroed in on the way cells manage external signals about prevailing...
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AudioStanford, CA—All living cells are held together by membranes, which provide a barrier to the transport of nutrients. They are also the...
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AudioStanford, CA—Plants spend their entire lifetime rooted to one spot. When faced with a bad situation, such as a swarm of hungry...
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AudioStanford, CA— Photosynthesis provides fixed carbon and energy for nearly all life on Earth, yet many aspects of this fascinating process...
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Revolutionary progress in understanding plant biology is being driven through advances in DNA sequencing technology. Carnegie plant scientists have played a key role in the sequencing and genome annotation efforts of the model plant Arabidopsis thaliana and the soil alga Chlamydomonas reinhardtii....
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Carnegie will receive Phase II funding through Grand Challenges Explorations, an initiative created by the Bill & Melinda Gates Foundation that enables individuals worldwide to test bold ideas to address persistent health and development challenges. Department of Plant Biology Director Wolf...
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Fresh water constitutes less than 1% of the surface water on earth, yet the importance of this simple molecule to all life forms is immeasurable. Water represents the most vital reagent for chemical reactions occurring in a cell. In plants, water provides the structural support necessary for plant...
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Wolf Frommer believes that understanding the basic mechanisms of plant life can help us solve problems in agriculture, the environment and medicine, and  even provide understanding of human diseases. He and his colleagues develop fundamental tools and technologies that advance our understanding of...
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Young investigator Martin Jonikas has broad ambitions: to transform our fundamental understanding of photosynthetic organisms by developing game-changing tools. In the long run, his lab aims to increase photosynthetic efficiency of crops, which could improve food production around the world. When...
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Plants are essential to life on Earth and provide us with food, fuel, clothing, and shelter.  Despite all this, we know very little about how they do what they do. Even for the best-studied species, such as Arabidopsis thaliana --a wild mustard studied in the lab--we know about less than 20% of...
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Washington, DC—The Carnegie Institution announced today that it is a grant recipient of the Grand Challenges Explorations initiative funded by the Bill & Melinda Gates Foundation. Wolf B. Frommer...
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A plant's roots grow and spread into the soil, taking up necessary water and minerals. The tip of a plant's root is a place of active cell division followed by cell elongation, with different zones...
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Stanford, CA— Four additional members of Stanford University’s faculty have been named Honorary Adjunct Staff Scientists at Carnegie’s Department of Plant Biology. Stanford’s Dominique Bergmann has...
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Carnegie Science, Carnegie Institution, Carnegie Institution for Science
December 14, 2016

Stanford, CA—Climate change and recent heat waves have put agricultural crops at risk, which means that understanding how plants respond to elevated temperatures is crucial for protecting our environment and food supply.

For many plants, even a small increase in average temperature can profoundly affect their growth and development. In the often-studied mustard plant called Arabidopsis, elevated temperatures cause the plants to grow longer stems and thinner leaves in order to cope with the heat stress.

New work led by Carnegie’s Zhiyong Wang uncovers the system by which plants regulate their response to heat differently between daytime and nighttime. It is published by

October 11, 2016

Stanford, CA—We generally think of inheritance as the genetic transfer from parent to offspring and that evolution moves toward greater complexity. But there are other ways that genes are transferred between organisms.

Sometimes a “host” organism can obtain genes from another organism that resides within its own cell (called an endosymbiont) through a process known as endosymbiotic gene transfer. At other times, an organism can obtain genes from a creature that lives in the surrounding environment, or from something that it eats, which is called horizontal gene transfer.

Furthermore, some levels of gene transfer can result in extensive loss of genes and genome reduction,

October 4, 2016

Stanford, CA— A feature thought to make plants sensitive to drought could actually hold the key to them coping with it better, according to new findings published by eLife, from Kathryn Barton of the Carnegie Institution for Science (Department of Plant Biology).

 Plants that are resistant to the hormone abscisic acid (ABA) have until now been understood to be bad at coping with drought. However, Barton and her team have now discovered ABA-resistant varieties that grow better than their normal neighbors when water is scarce. The new research suggests breeders should explore them for “stay green” traits.

 “When breeders are looking for plants able to withstand drought, they

September 22, 2016

Stanford, CA—The Howard Hughes Medical Institute (HHMI) and the Simons Foundation have awarded José Dinneny, of Carnegie’s Department of Plant Biology an HHMI-Simons Faculty Scholar grant. He is one of 84 scientists chosen out of some 1,400 applicants in a new program that the Howard Hughes Medical Institute (HHMI), the Simons Foundation, and the Bill & Melinda Gates Foundation have created. The grant will provide $250,000 per year for five years, in addition to overhead expenses, for an award total of $1,500,000.

The award will be funded by the Simons Foundation and administered by the Howard Hughes Medical Institute. Faculty Scholars are “early-career scientists who have

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Revolutionary progress in understanding plant biology is being driven through advances in DNA sequencing technology. Carnegie plant scientists have played a key role in the sequencing and genome annotation efforts of the model plant Arabidopsis thaliana and the soil alga Chlamydomonas reinhardtii. Now that many genomes from algae to mosses and trees are publicly available, this information can be mined using bioinformatics to build models to understand gene function and ultimately for designing plants for a wide spectrum of applications.

 Carnegie researchers have pioneered a genome-wide gene association network Aranet that can assign functions to genes for which no function had

Today, humanity is increasingly aware of the impact it has on the environment and the difficulties caused when the environment impacts our communities. Environmental change can be particularly harsh when the plants we use for food, fuel, feed and fiber are affected by this change. High salinity is an agricultural contaminant of increasing significance. Not only does this limit the land available for use in agriculture, but in land that has been used for generations, the combination of irrigation and evaporation gradually leads to increasing soil salinity.

The Dinneny lab focuses on understanding how developmental processes such as cell-type specification regulate responses to

Fresh water constitutes less than 1% of the surface water on earth, yet the importance of this simple molecule to all life forms is immeasurable. Water represents the most vital reagent for chemical reactions occurring in a cell. In plants, water provides the structural support necessary for plant growth. It acts as the carrier for nutrients absorbed from the soil and transported to the shoot. It also provides the chemical components necessary to generate sugar and biomass from light and carbon dioxide during photosynthesis. While the importance of water to plants is clear, an understanding as to how plants perceive water is limited. Most studies have focused on environmental conditions

Carnegie researchers recently constructed genetically encoded FRET sensors for a variety of important molecules such as glucose and glutamate. The centerpiece of these sensors is a recognition element derived from the superfamily of bacterial binding protiens called periplasmic binding protein (PBPs), proteins that are primary receptors for moving chemicals  for hundreds of different small molecules. PBPs are ideally suited for sensor construction. The scientists fusie individual PBPs with a pair of variants and produced a large set of sensors, e.g. for sugars like maltose, ribose and glucose or for the neurotransmitter glutamate. These sensors have been adopted for measurement of sugar

One way to adapt to climate change is to understand how plants can thrive in the changing environment. José Dinneny looks at the mechanisms that control environmental responses in plants, including responses to salty soils and different moisture conditions—work that provides the foundation for developing crops for the changing climate.

The Dinneny  lab focuses on understanding how developmental processes such as cell-type specification regulate responses to environmental change. Most studies have considered the organ or even the whole organism as a single responsive unit and ignore the potential diversity of responses by the various cell-types composing an organism. Dinneny has

Understanding how plants grow can lead to improving crops.  Plant scientist Kathryn Barton, who joined Carnegie in 2001, investigates just that: what controls the plant’s body plan, from  the time it’s an embryo to its adult leaves. These processes include how plant parts form different orientations, from top to bottom, and different poles. She looks at regulation by small RNA’s, the function of small so-called Zipper proteins, and how hormone biosynthesis and response controls the plant’s growth.

Despite an enormous variety in leaf shape and arrangement, the basic body plan of plants is about the same: stems and leaves alternate in repeating units. The structure responsible for

Wolf Frommer believes that understanding the basic mechanisms of plant life can help us solve problems in agriculture, the environment and medicine, and  even provide understanding of human diseases. He and his colleagues develop fundamental tools and technologies that advance our understanding of glucose, sucrose, ammonium, amino acid, and nucleotide transport in plants.

Transport proteins are responsible for moving materials such as nutrients and metabolic products through a cell’s outer membrane, which seals and protects all living cells, to the cell’s interior. These transported molecules include sugars, which can be used to fuel growth or to respond to chemical signals of

Matthew Evans wants to provide new tools for plant scientists to engineer better seeds for human needs. He focuses on one of the two phases to their life cycle. In the first phase, the sporophyte is the diploid generation—that is with two similar sets of chromosomes--that undergoes meiosis to produce cells called spores. Each spore divides forming a single set of chromosomes (haploid) --the gametophyte--which produces the sperm and egg cells.

Evans studies how the haploid genome is required for normal egg and sperm function. In flowering plants, the female gametophyte, called the embryo sac, consists of four cell types: the egg cell, the central cell, and two types of supporting