Washington, D.C. — Plant science is key to addressing the major challenges facing humanity in the 21st Century, according to Carnegie’s David Ehrhardt and Wolf Frommer. In a Perspective published in...
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Stanford, CA—The major difference between plant and animal cells is the photosynthetic process, which converts light energy into chemical energy. When light isn’t available, energy is generated by...
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Stanford, CA— Along with photosynthesis, the plant cell wall is one of the features that most set plants apart from animals. A structural molecule called cellulose is necessary for the manufacture of...
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Stanford, CA— Plant's leaves are sealed with a gas-tight wax layer to prevent water loss. Plants breathe through microscopic pores called stomata (Greek for mouths) on the surfaces of leaves. Over 40...
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Stanford, CA— Plant roots are fascinating plant organs – they not only anchor the plant, but are also the world’s most efficient mining companies. Roots live in darkness and direct the activities of...
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  Stanford, CA – Scientists at Carnegie’s Department of Plant Biology have made the first real-time observations of sugars in the cells of intact and living plant tissues. With the...
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Fresh water constitutes less than 1% of the surface water on earth, yet the importance of this simple molecule to all life forms is immeasurable. Water represents the most vital reagent for chemical reactions occurring in a cell. In plants, water provides the structural support necessary for plant...
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Revolutionary progress in understanding plant biology is being driven through advances in DNA sequencing technology. Carnegie plant scientists have played a key role in the sequencing and genome annotation efforts of the model plant Arabidopsis thaliana and the soil alga ...
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Today, humanity is increasingly aware of the impact it has on the environment and the difficulties caused when the environment impacts our communities. Environmental change can be particularly harsh when the plants we use for food, fuel, feed and fiber are affected by this change. High salinity is...
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Matthew Evans wants to provide new tools for plant scientists to engineer better seeds for human needs. He focuses on one of the two phases to their life cycle. In the first phase, the sporophyte is the diploid generation—that is with two similar sets of chromosomes--that undergoes meiosis to...
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Arthur Grossman believes that the future of plant science depends on research that spans ecology, physiology, molecular biology and genomics. As such, work in his lab has been extremely diverse. He identifies new functions associated with photosynthetic processes, the mechanisms of coral bleaching...
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Plants are not as static as you think. David Ehrhardt combines confocal microscopy with novel visualization methods to see the three-dimensional movement  within live plant cells to reveal the other-worldly cell choreography that makes up plant tissues. These methods allow his group to explore...
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A plant's roots grow and spread into the soil, taking up necessary water and minerals. The tip of a plant's root is a place of active cell division followed by cell elongation, with different...
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Science News magazine has selected José Dinneny, of Carnegie’s Department of Plant Biology, as one of ten young scientists to watch in 2017. The researchers were selected because they...
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Plants have tiny pores on their leaves called stomata—Greek for mouths—through which they take in carbon dioxide from the air and from which water evaporates. New work reveals ways that...
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Explore Carnegie Science

Chlamydomonas
March 21, 2019

Palo Alto, CA—The creation of new library of mutants of the single-celled photosynthetic green alga Chlamydomonas reinhardtii enabled a Carnegie- and Princeton University-led team of plant scientists to identify more than 300 genes that are potentially required for photosynthesis. Photosynthesis is the process by which plants, algae, and some bacteria convert energy from sunlight into carbohydrates—filling our planet’s atmosphere with oxygen as a byproduct.

Their findings are published this week in Nature Genetics.

Chlamydomonas represents a group of algae that are found around the globe in fresh and saltwater, moist soil, and even snow. They are

February 19, 2019

Heather Meyer, a postdoctoral fellow in David Ehrhardt’s Plant Biology lab since 2016, has been awarded Carnegie’s twelfth Postdoctoral Innovation and Excellence Award. These prizes are given to postdocs for their exceptionally creative approaches to science, strong mentoring, and contributing to the sense of campus community. The nominations are made by the departments and are chosen by the Office of the President. The recipients receive a cash prize and are celebrated at an event at their departments.  

Heather initiated a pioneering scientific project to identify the molecular mechanisms that plants use to sense and respond to seasonal temperatures in order to

February 12, 2019

Washington, DC— Carnegie’s Winslow Briggs, a giant in the field of plant biology who explained how seedlings grow toward light, died on February 11 at Stanford University Medical Center. He was 90.

Briggs joined Carnegie as the Director of the Department of Plant Biology in 1973 after teaching both at Harvard University—where he completed his bachelor’s degree, master’s degree, and Ph.D.—and at Stanford University. He held the position for two decades, establishing himself as a global leader in plant genetics and physiology, publishing landmark research on the molecular mechanisms that plants and other organisms use to sense and respond to light

Sue Rhee, Thomas Clandinin and Miriam B. Goodman discuss the NeuroPlant project over a tobacco plant in the greenhouse. (Image credit: L.A. Cicero)
January 22, 2019

Stanford, CA—For millennia, humanity has used medicinal plants and plant-based compounds to treat a variety of neurological ailments including epilepsy, mania, migraines, and bipolar disorder. Now a team of researchers from Carnegie and Stanford University is using microscopic worms to understand what these plant-derived molecules are and how they affect the brain’s biochemistry.

Called the NeuroPlant project, these efforts could lead to new, more efficient ways to develop drugs to treat a variety of neurological and psychiatric diseases in humans. Their work is funded by a Big Ideas grant from the Wu Tsai Neurosciences Institute.

“We’re interested

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Carnegie researchers recently constructed genetically encoded FRET sensors for a variety of important molecules such as glucose and glutamate. The centerpiece of these sensors is a recognition element derived from the superfamily of bacterial binding protiens called periplasmic binding protein (PBPs), proteins that are primary receptors for moving chemicals  for hundreds of different small molecules. PBPs are ideally suited for sensor construction. The scientists fusie individual PBPs with a pair of variants and produced a large set of sensors, e.g. for sugars like maltose, ribose and glucose or for the neurotransmitter glutamate. These sensors have been adopted for measurement of

Revolutionary progress in understanding plant biology is being driven through advances in DNA sequencing technology. Carnegie plant scientists have played a key role in the sequencing and genome annotation efforts of the model plant Arabidopsis thaliana and the soil alga Chlamydomonas reinhardtii. Now that many genomes from algae to mosses and trees are publicly available, this information can be mined using bioinformatics to build models to understand gene function and ultimately for designing plants for a wide spectrum of applications.

 Carnegie researchers have pioneered a genome-wide gene association network Aranet that can assign functions

Today, humanity is increasingly aware of the impact it has on the environment and the difficulties caused when the environment impacts our communities. Environmental change can be particularly harsh when the plants we use for food, fuel, feed and fiber are affected by this change. High salinity is an agricultural contaminant of increasing significance. Not only does this limit the land available for use in agriculture, but in land that has been used for generations, the combination of irrigation and evaporation gradually leads to increasing soil salinity.

The Dinneny lab focuses on understanding how developmental processes such as cell-type specification regulate responses to

Carnegie will receive Phase II funding through Grand Challenges Explorations, an initiative created by the Bill & Melinda Gates Foundation that enables individuals worldwide to test bold ideas to address persistent health and development challenges. Department of Plant Biology Director Wolf Frommer,  with a team of researchers from the International Rice Research Institute, Kansas State University, and Iowa State University, will continue to pursue an innovative global health research project, titled “Transformative Strategy for Controlling Rice Blight.”

Rice bacterial blight is one of the major challenges to food security, and this project aims to

Arthur Grossman believes that the future of plant science depends on research that spans ecology, physiology, molecular biology and genomics. As such, work in his lab has been extremely diverse. He identifies new functions associated with photosynthetic processes, the mechanisms of coral bleaching and the impact of temperature and light on the bleaching process.

He also has extensively studied the blue-green algae Chlamydomonas genome and is establishing methods for examining the set of RNA molecules and the function of proteins involved in their photosynthesis and acclimation. He also studies the regulation of sulfur metabolism in green algae and plants.  

Grossman

Devaki Bhaya wants to understand how environmental stressors, such as light, nutrients, and viral attacks are sensed by and affect photosynthetic microorganisms. She is also interested in understanding the mechanisms behind microorganism movements, and how individuals in groups communicate, evolve, share resources. To these ends, she focuses on one-celled, aquatic cyanobacteria, in the lab with model organisms and with organisms in naturally occurring communities.

 Phototaxis is the ability of organisms to move directionally in response to a light source.  Many cyanobacteria exhibit phototaxis, both towards and away from light. The ability to move into optimal light

Plants are essential to life on Earth and provide us with food, fuel, clothing, and shelter.  Despite all this, we know very little about how they do what they do. Even for the best-studied species, such as Arabidopsis thaliana --a wild mustard studied in the lab--we know about less than 20% of what its genes do and how or why they do it. And understanding this evolution can help develop new crop strains to adapt to climate change.  

Sue Rhee wants to uncover the molecular mechanisms underlying adaptive traits in plants to understand how these traits evolved. A bottleneck has been the limited understanding of the functions of most plant genes. Rhee’s group is

Plants are not as static as you think. David Ehrhardt combines confocal microscopy with novel visualization methods to see the three-dimensional movement  within live plant cells to reveal the other-worldly cell choreography that makes up plant tissues. These methods allow his group to explore cell-signaling and cell-organizational events as they unfold.

These methods allow his lab to investigate plant cell development and structure and molecular genetics to understand the organization and dynamic behaviors of molecules and organelles. The group tackles how cells generate asymmetries and specific shapes. A current focus is how the cortical microtubule cytoskeleton— an