Washington, D.C. —Until now it has not been clear how salt, a scourge to agriculture, halts the growth of the plant-root system. A team of researchers, led by the Carnegie Institution’s...
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Stanford, CA — Plants grow upward from a tip of undifferentiated tissue called the shoot apical meristem. As the tip extends, stem cells at the center of the meristem divide and increase in numbers....
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Washington, DC—The Carnegie Institution announced today that it is a grant recipient of the Grand Challenges Explorations initiative funded by the Bill & Melinda Gates Foundation. Wolf B. Frommer...
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Stanford, CA —Light is not only the source of a plant’s energy, but also an environmental signal that instructs the growth behavior of plants. As a result, a plant’s sensitivity to light is of great...
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Stanford, CA—The scientific community needs to make a 10-year, $100 billion investment in food and energy security, says Carnegie’s Wolf Frommer and Tom Brutnell of the Donald Danforth Plant Science...
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Washington, D.C.—The American Society for Plant Biology (ASPB) awarded Wolf B. Frommer, director of Carnegie’s Department of Plant Biology, the Lawrence Bogorad Award for Excellence in Plant Biology...
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Stanford, CA — The Plant Metabolic Network (http://www.plantcyc.org/), which is based at Carnegie’s Department of Plant Biology, has launched four new online...
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Washington, D.C. — Plant science is key to addressing the major challenges facing humanity in the 21st Century, according to Carnegie’s David Ehrhardt and Wolf Frommer. In a Perspective published in...
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Carnegie will receive Phase II funding through Grand Challenges Explorations, an initiative created by the Bill & Melinda Gates Foundation that enables individuals worldwide to test bold ideas to address persistent health and development challenges. Department of Plant Biology Director...
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Today, humanity is increasingly aware of the impact it has on the environment and the difficulties caused when the environment impacts our communities. Environmental change can be particularly harsh when the plants we use for food, fuel, feed and fiber are affected by this change. High salinity is...
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Carnegie researchers recently constructed genetically encoded FRET sensors for a variety of important molecules such as glucose and glutamate. The centerpiece of these sensors is a recognition element derived from the superfamily of bacterial binding protiens called periplasmic binding protein (...
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Plants are not as static as you think. David Ehrhardt combines confocal microscopy with novel visualization methods to see the three-dimensional movement  within live plant cells to reveal the other-worldly cell choreography that makes up plant tissues. These methods allow his group to explore...
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Matthew Evans wants to provide new tools for plant scientists to engineer better seeds for human needs. He focuses on one of the two phases to their life cycle. In the first phase, the sporophyte is the diploid generation—that is with two similar sets of chromosomes--that undergoes meiosis to...
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Plants are essential to life on Earth and provide us with food, fuel, clothing, and shelter.  Despite all this, we know very little about how they do what they do. Even for the best-studied species, such as Arabidopsis thaliana --a wild mustard studied in the lab--we know about less than 20%...
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Stanford, CA— Coral reefs are tremendously important for ocean biodiversity, as well as for the economic and aesthetic value they provide to their surrounding communities. Unfortunately they have...
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Explore Carnegie Science

February 19, 2019

Heather Meyer, a postdoctoral fellow in David Ehrhardt’s Plant Biology lab since 2016, has been awarded Carnegie’s twelfth Postdoctoral Innovation and Excellence Award. These prizes are given to postdocs for their exceptionally creative approaches to science, strong mentoring, and contributing to the sense of campus community. The nominations are made by the departments and are chosen by the Office of the President. The recipients receive a cash prize and are celebrated at an event at their departments.  

Heather initiated a pioneering scientific project to identify the molecular mechanisms that plants use to sense and respond to seasonal temperatures in order to

February 12, 2019

Washington, DC— Carnegie’s Winslow Briggs, a giant in the field of plant biology who explained how seedlings grow toward light, died on February 11 at Stanford University Medical Center. He was 90.

Briggs joined Carnegie as the Director of the Department of Plant Biology in 1973 after teaching both at Harvard University—where he completed his bachelor’s degree, master’s degree, and Ph.D.—and at Stanford University. He held the position for two decades, establishing himself as a global leader in plant genetics and physiology, publishing landmark research on the molecular mechanisms that plants and other organisms use to sense and respond to light

Sue Rhee, Thomas Clandinin and Miriam B. Goodman discuss the NeuroPlant project over a tobacco plant in the greenhouse. (Image credit: L.A. Cicero)
January 22, 2019

Stanford, CA—For millennia, humanity has used medicinal plants and plant-based compounds to treat a variety of neurological ailments including epilepsy, mania, migraines, and bipolar disorder. Now a team of researchers from Carnegie and Stanford University is using microscopic worms to understand what these plant-derived molecules are and how they affect the brain’s biochemistry.

Called the NeuroPlant project, these efforts could lead to new, more efficient ways to develop drugs to treat a variety of neurological and psychiatric diseases in humans. Their work is funded by a Big Ideas grant from the Wu Tsai Neurosciences Institute.

“We’re interested

A bright field image of the anemone Aiptasia populated with its symbiotic algae.
December 6, 2018

Stanford, CA—How much of the ability of a coral reef to withstand stressful conditions is influenced by the type of algae that the corals hosts?

Corals are marine invertebrates from the phylum called cnidarians that build large exoskeletons from which colorful reefs are constructed. But this reef-building is only possible because of a mutually beneficial relationship between the coral and various species of single-celled algae called dinoflagellates that live inside the cells of coral polyps.

The algae are photosynthetic—meaning capable of converting the Sun’s energy into chemical energy for food, just like plants. And the exchange of nutrients between the

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Fresh water constitutes less than 1% of the surface water on earth, yet the importance of this simple molecule to all life forms is immeasurable. Water represents the most vital reagent for chemical reactions occurring in a cell. In plants, water provides the structural support necessary for plant growth. It acts as the carrier for nutrients absorbed from the soil and transported to the shoot. It also provides the chemical components necessary to generate sugar and biomass from light and carbon dioxide during photosynthesis. While the importance of water to plants is clear, an understanding as to how plants perceive water is limited. Most studies have focused on environmental conditions

Carnegie researchers recently constructed genetically encoded FRET sensors for a variety of important molecules such as glucose and glutamate. The centerpiece of these sensors is a recognition element derived from the superfamily of bacterial binding protiens called periplasmic binding protein (PBPs), proteins that are primary receptors for moving chemicals  for hundreds of different small molecules. PBPs are ideally suited for sensor construction. The scientists fusie individual PBPs with a pair of variants and produced a large set of sensors, e.g. for sugars like maltose, ribose and glucose or for the neurotransmitter glutamate. These sensors have been adopted for measurement of

Carnegie will receive Phase II funding through Grand Challenges Explorations, an initiative created by the Bill & Melinda Gates Foundation that enables individuals worldwide to test bold ideas to address persistent health and development challenges. Department of Plant Biology Director Wolf Frommer,  with a team of researchers from the International Rice Research Institute, Kansas State University, and Iowa State University, will continue to pursue an innovative global health research project, titled “Transformative Strategy for Controlling Rice Blight.”

Rice bacterial blight is one of the major challenges to food security, and this project aims to

Revolutionary progress in understanding plant biology is being driven through advances in DNA sequencing technology. Carnegie plant scientists have played a key role in the sequencing and genome annotation efforts of the model plant Arabidopsis thaliana and the soil alga Chlamydomonas reinhardtii. Now that many genomes from algae to mosses and trees are publicly available, this information can be mined using bioinformatics to build models to understand gene function and ultimately for designing plants for a wide spectrum of applications.

 Carnegie researchers have pioneered a genome-wide gene association network Aranet that can assign functions

Matthew Evans wants to provide new tools for plant scientists to engineer better seeds for human needs. He focuses on one of the two phases to their life cycle. In the first phase, the sporophyte is the diploid generation—that is with two similar sets of chromosomes--that undergoes meiosis to produce cells called spores. Each spore divides forming a single set of chromosomes (haploid) --the gametophyte--which produces the sperm and egg cells.

Evans studies how the haploid genome is required for normal egg and sperm function. In flowering plants, the female gametophyte, called the embryo sac, consists of four cell types: the egg cell, the central cell, and two types of

Plants are essential to life on Earth and provide us with food, fuel, clothing, and shelter.  Despite all this, we know very little about how they do what they do. Even for the best-studied species, such as Arabidopsis thaliana --a wild mustard studied in the lab--we know about less than 20% of what its genes do and how or why they do it. And understanding this evolution can help develop new crop strains to adapt to climate change.  

Sue Rhee wants to uncover the molecular mechanisms underlying adaptive traits in plants to understand how these traits evolved. A bottleneck has been the limited understanding of the functions of most plant genes. Rhee’s group is

Arthur Grossman believes that the future of plant science depends on research that spans ecology, physiology, molecular biology and genomics. As such, work in his lab has been extremely diverse. He identifies new functions associated with photosynthetic processes, the mechanisms of coral bleaching and the impact of temperature and light on the bleaching process.

He also has extensively studied the blue-green algae Chlamydomonas genome and is establishing methods for examining the set of RNA molecules and the function of proteins involved in their photosynthesis and acclimation. He also studies the regulation of sulfur metabolism in green algae and plants.  

Grossman

Devaki Bhaya wants to understand how environmental stressors, such as light, nutrients, and viral attacks are sensed by and affect photosynthetic microorganisms. She is also interested in understanding the mechanisms behind microorganism movements, and how individuals in groups communicate, evolve, share resources. To these ends, she focuses on one-celled, aquatic cyanobacteria, in the lab with model organisms and with organisms in naturally occurring communities.

 Phototaxis is the ability of organisms to move directionally in response to a light source.  Many cyanobacteria exhibit phototaxis, both towards and away from light. The ability to move into optimal light