Genetics & Developmental Biology Stories
Cells often face low-oxygen conditions at night. When this happens, some organisms such as the single-cell alga Chlamydomonas are able to generate cellular energy from the breakdown of sugars...
Nutrition and metabolism are closely linked with reproductive health. Several reproductive disorders have been linked to malnutrition, diabetes, and obesity. Furthermore, fasting in numerous species...
Baltimore, MD— Nutrition and metabolism are closely linked with reproductive health. Several reproductive disorders including polycystic ovary syndrome, amenorrhea, and ovarian cancer have been...
Baltimore, MD—The newest member of the staff at the Carnegie Department of Embryology, Junior Investigator Zhao Zhang, received the prestigious Larry Sandler Memorial Award at the 56th Annual...
February 11, 2015
Dr. Douglas Koshland,
University of California Berkeley, Department of Molecular & Cell Biology
Remarkable organisms exemplify extremes in the spectrum of life, like transparent...
We would not expect a baby to join a team or participate in social situations that require sophisticated communication. Yet, most developmental biologists have assumed that young cells, only recently...
Baltimore MD— We would not expect a baby to join a team or participate in social situations that require sophisticated communication. Yet, most developmental biologists have assumed that young...
Tuesday, November 25, 2014, Baltimore, MD—Biologist Marnie Halpern of Carnegie’s Department of Embryology has been named a Fellow of the American Association for the Advancement of...
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The Spradling laboratory studies the biology of reproduction. By unknown means eggs reset the normally irreversible processes of differentiation and aging. The fruit fly Drosophila provides a favorable multicellular system for molecular genetic studies. The lab focuses on several aspects of egg...
In mammals, most lipids, such as fatty acids and cholesterol, are absorbed into the body via the small intestine. The complexity of the cells and fluids that inhabit this organ make it very difficult to study in a laboratory setting. The goal of the Farber lab is to better understand the cell and...
The Marnie Halpern laboratory studies how left-right differences arise in the developing brain and discovers the genes that control this asymmetry. Using the tiny zebrafish, Danio rerio, they explores how regional specializations occur within the neural tube, the embryonic tissue that develops into...
Staff Associate Kamena Kostova joined the Department of Embryology in November 2018. She studies ribosomes, the factory-like structures inside cells that produce proteins. Scientists have known about ribosome structure, function, and biogenesis for some time. But, a major unanswered question...
Frederick Tan holds a unique position at Embryology in this era of high-throughput sequencing where determining DNA and RNA sequences has become one of the most powerful technologies in biology. DNA provides the basic code shared by all our cells to program our development. While there are about 30...
Integrity of hereditary material—the genome —is critical for species survival. Genomes need protection from agents that can cause mutations affecting DNA coding, regulatory functions, and duplication during cell division. DNA sequences called transposons, or jumping genes (discovered by...
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Almost half of our DNA sequences are made up of jumping genes. Jumping genes jump around the genome in developing sperm and egg cells and are important to evolution, but can also cause disease...
The buildup of scar tissue makes recovery from torn rotator cuffs, jumper’s knee, and other tendon injuries a painful, challenging process, often leading to secondary tendon ruptures. New...
What can our micobiome's response to antibiotics teach us about species interactions in nature? New work from Carnegie Embryology and Stanford University set out to answer...
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