Genetics & Developmental Biology Stories
Baltimore MD—Almost half of our DNA sequences are made up of jumping genes—also known as transposons. They jump around the genome in developing sperm and egg cells and are important to...
Baltimore, MD—A tremendous amount of genetic material must be packed into the nucleus of every cell—a tiny compartment. One of the biggest challenges in biology is to understand how...
Baltimore, MD—Allan C. Spradling, Director Emeritus of Carnegie’s Department of Embryology, has been awarded the 23rd March of Dimes and Richard B. Johnson, Jr., MD Prize in...
Washington, DC—Not too long ago, biologists would induce mutations in an entire genome, isolate an organism that displayed a resulting disease or abnormality that they wanted to study, and then...
Baltimore, MD— The brain is the body’s mission control center, sending messages to the other organs about how to respond to various external and internal stimuli. Located in the forebrain...
Washington, D.C.--Yixian Zheng has been selected to direct Carnegie’s Department of Embryology in Baltimore, Maryland. She has been Acting Director since February 1st of 2016.
Carnegie...
Washington, D.C.—BioEYES was accepted to participate in a National Science Foundation (NSF) video competition on May 15-22, 2017. BioEYES supporters are encouraged to go to the competition...
On Tuesday night, George Church told us that a fascination with animatronic Abraham Lincoln at the 1964 World’s Fair partially inspired him to become a scientist.
This seems fitting, somehow,...
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The Gall laboratory studies all aspects of the cell nucleus, particularly the structure of chromosomes, the transcription and processing of RNA, and the role of bodies inside the cell nucleus, especially the Cajal body (CB) and the histone locus body (HLB).
Much of the work makes use of the giant...
Approximately half of the gene sequences of human and mouse genomes comes from so-called mobile elements—genes that jump around the genome. Much of this DNA is no longer capable of moving, but is likely “auditioning” perhaps as a regulator of gene function or in homologous...
In mammals, most lipids, such as fatty acids and cholesterol, are absorbed into the body via the small intestine. The complexity of the cells and fluids that inhabit this organ make it very difficult to study in a laboratory setting. The goal of the Farber lab is to better understand the cell and...
The first step in gene expression is the formation of an RNA copy of its DNA. This step, called transcription, takes place in the cell nucleus. Transcription requires an enzyme called RNA polymerase to catalyze the synthesis of the RNA from the DNA template. This, in addition to other processing...
Integrity of hereditary material—the genome —is critical for species survival. Genomes need protection from agents that can cause mutations affecting DNA coding, regulatory functions, and duplication during cell division. DNA sequences called transposons, or jumping genes (discovered by...
The Ludington lab investigates complex ecological dynamics from microbial community interactions using the fruit fly Drosophila melanogaster. The fruit fly gut carries numerous microbial species, which can be cultured in the lab. The goal is to understand the gut ecology...
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Every high school biology class learns about the process of mitosis, the series of steps through which a cell divides itself into two daughter cells, each with the same genetic material. Mitosis...
Baltimore, MD— As we age, the function and regenerative abilities of skeletal muscles deteriorate, which means it is difficult for the elderly to recover from injury or surgery. New work from...
In humans, the gut microbiome is an ecosystem of hundreds to thousands of microbial species living within the gastrointestinal tract, influencing health and even longevity. As interest in studying...
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