Genetics & Developmental Biology Stories
Baltimore, MD— As we age, the function and regenerative abilities of skeletal muscles deteriorate, which means it is difficult for the elderly to recover from injury or surgery. New work from...
Baltimore, MD—New work from Carnegie’s Allan Spradling and Lei Lei demonstrates that mammalian egg cells gain crucial cellular components at an early stage from their undifferentiated...
Washington, D.C.—Matthew Sieber, a postdoctoral fellow at the Department of Embryology, has been honored for his extraordinary accomplishments, through a new program that recognizes exceptional...
Baltimore, MD— Reproduction is highly dependent on diet and the ability to use nutrients to grow and generate energy. This is clearly seen in women, who must provide all the nutritional...
San Diego, CA— Ghosts are not your typical cell biology research subjects. But scientists at the Carnegie Institution for Science and the National Institute of Child Health and Human...
The American Society for Cell Biology profiles Yixian Zheng and her recent papers on the elusive spindle matrix. "Zheng’s lab identifies new regulators in spindle assembly, all...
Two researchers, Martin Jonikas of Carnegie’s Department of Plant Biology and Zhao Zhang of the Department of Embryology, have been awarded the New Innovator and Early Independence Awards,...
Baltimore, MD— Every high school biology class learns about the tiny cells that comprise our bodies, as well as about many of the diverse actions that they perform. One of these actions is...
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The Fan laboratory studies the molecular mechanisms that govern mammalian development, using the mouse as a model. They use a combination of biochemical, molecular and genetic approaches to identify and characterize signaling molecules and pathways that control the development and maintenance of...
The Gall laboratory studies all aspects of the cell nucleus, particularly the structure of chromosomes, the transcription and processing of RNA, and the role of bodies inside the cell nucleus, especially the Cajal body (CB) and the histone locus body (HLB).
Much of the work makes use of the giant...
The Marnie Halpern laboratory studies how left-right differences arise in the developing brain and discovers the genes that control this asymmetry. Using the tiny zebrafish, Danio rerio, they explores how regional specializations occur within the neural tube, the embryonic tissue that develops into...
The Ludington lab investigates complex ecological dynamics from microbial community interactions using the fruit fly Drosophila melanogaster. The fruit fly gut carries numerous microbial species, which can be cultured in the lab. The goal is to understand the gut ecology...
There is a lot of folklore about left-brain, right-brain differences—the right side of the brain is supposed to be the creative side, while the left is the logical half. But it’s much more complicated than that. Marnie Halpern studies how left-right differences arise in the developing...
In mammals, most lipids, such as fatty acids and cholesterol, are absorbed into the body via the small intestine. The complexity of the cells and fluids that inhabit this organ make it very difficult to study in a laboratory setting. The goal of the Farber lab is to better understand the cell and...
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Baltimore, MD— A woman’s supply of eggs is a precious commodity because only a few hundred mature eggs can be produced throughout her lifetime and each must be as free as possible from genetic damage...
We would not expect a baby to join a team or participate in social situations that require sophisticated communication. Yet, most developmental biologists have assumed that young cells, only recently...
New work led by Carnegie’s Steven Farber, with help from Yixian Zheng’s lab, sheds light on how form follows function for intestinal cells responding to high-fat foods that are rich in...
