Genetics & Developmental Biology Stories
Baltimore, MD—New work from Carnegie’s Allan Spradling and Lei Lei demonstrates that mammalian egg cells gain crucial cellular components at an early stage from their undifferentiated...
Washington, D.C.—Matthew Sieber, a postdoctoral fellow at the Department of Embryology, has been honored for his extraordinary accomplishments, through a new program that recognizes exceptional...
Baltimore, MD— Reproduction is highly dependent on diet and the ability to use nutrients to grow and generate energy. This is clearly seen in women, who must provide all the nutritional...
San Diego, CA— Ghosts are not your typical cell biology research subjects. But scientists at the Carnegie Institution for Science and the National Institute of Child Health and Human...
The American Society for Cell Biology profiles Yixian Zheng and her recent papers on the elusive spindle matrix. "Zheng’s lab identifies new regulators in spindle assembly, all...
Two researchers, Martin Jonikas of Carnegie’s Department of Plant Biology and Zhao Zhang of the Department of Embryology, have been awarded the New Innovator and Early Independence Awards,...
Baltimore, MD— Every high school biology class learns about the tiny cells that comprise our bodies, as well as about many of the diverse actions that they perform. One of these actions is...
Baltimore, MD—Carnegie’s BioEYES K-12 science educational program launches a new center sponsored by the University of Utah, Department of Pediatrics, Pediatric Research Enterprise. The...
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Approximately half of the gene sequences of human and mouse genomes comes from so-called mobile elements—genes that jump around the genome. Much of this DNA is no longer capable of moving, but is likely “auditioning” perhaps as a regulator of gene function or in homologous...
The thyroid gland secretes thyroxine (TH), a hormone essential for the growth and development of all vertebrates including humans. To understand TH action, the Donald Brown lab studies one of the most dramatic roles of the hormone, the control of amphibian metamorphosis—the process by which a...
The Marnie Halpern laboratory studies how left-right differences arise in the developing brain and discovers the genes that control this asymmetry. Using the tiny zebrafish, Danio rerio, they explores how regional specializations occur within the neural tube, the embryonic tissue that develops into...
In mammals, most lipids, such as fatty acids and cholesterol, are absorbed into the body via the small intestine. The complexity of the cells and fluids that inhabit this organ make it very difficult to study in a laboratory setting. The goal of the Farber lab is to better understand the cell and...
Staff Associate Kamena Kostova joined the Department of Embryology in November 2018. She studies ribosomes, the factory-like structures inside cells that produce proteins. Scientists have known about ribosome structure, function, and biogenesis for some time. But, a major unanswered question...
Allan Spradling is a Howard Hughes Medical Institute Investigator and director of the Department of Embryology. His laboratory studies the biology of reproduction particularly egg cells, which are able to reset the normally irreversible processes of differentiation and aging that govern all somatic...
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Baltimore, MD— A woman’s supply of eggs is a precious commodity because only a few hundred mature eggs can be produced throughout her lifetime and each must be as free as possible from genetic damage...
The American Society for Cell Biology profiles Yixian Zheng and her recent papers on the elusive spindle matrix. "Zheng’s lab identifies new regulators in spindle assembly, all...
Baltimore, MD—A first-of-its-kind study on almost 20,000 K-12 underrepresented public school students shows that Project BioEYES, based at Carnegie’s Department of Embryology, is effective at...
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