Genetics & Developmental Biology Stories
Baltimore, MD—The buildup of scar tissue makes recovery from torn rotator cuffs, jumper’s knee, and other tendon injuries a painful, challenging process, often leading to secondary tendon...
Baltimore, MD— Carnegie biologist Kamena Kostova has been selected for the...
Washington, DC— An age-related decline in recovery from muscle injury can be traced to a protein that suppresses the special ability of muscle stem cells to build new muscles, according to work...
Baltimore, MD—A newly developed technique that shows artery clogging fat-and-protein complexes in live fish gave investigators from Carnegie, Johns Hopkins University, and the Mayo Clinic a...
Baltimore, MD—How do the communities of microbes living in our gastrointestinal systems affect our health? Carnegie’s Will Ludington was part of a team that helped answer this question....
Meredith Wilson, a postdoctoral associate in Steve Farber’s lab at the Department of Embryology, has been awarded Carnegie’s thirteenth Postdoctoral Innovation and Excellence Award. These...
Washington, DC—Aging-related inflammation can drive the decline of a critical structural protein called lamin-B1, which contributes to diminished immune function in the thymus, according to...
Baltimore, MD—This week Carnegie’s Steve Farber will be recognized by New England Biolabs Inc. with its Passion in Science Award in the category of Mentorship and Advocacy. The company,...
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The Fan laboratory studies the molecular mechanisms that govern mammalian development, using the mouse as a model. They use a combination of biochemical, molecular and genetic approaches to identify and characterize signaling molecules and pathways that control the development and maintenance of...
The Gall laboratory studies all aspects of the cell nucleus, particularly the structure of chromosomes, the transcription and processing of RNA, and the role of bodies inside the cell nucleus, especially the Cajal body (CB) and the histone locus body (HLB).
Much of the work makes use of the giant...
Approximately half of the gene sequences of human and mouse genomes comes from so-called mobile elements—genes that jump around the genome. Much of this DNA is no longer capable of moving, but is likely “auditioning” perhaps as a regulator of gene function or in homologous...
Frederick Tan holds a unique position at Embryology in this era of high-throughput sequencing where determining DNA and RNA sequences has become one of the most powerful technologies in biology. DNA provides the basic code shared by all our cells to program our development. While there are about 30...
There is a lot of folklore about left-brain, right-brain differences—the right side of the brain is supposed to be the creative side, while the left is the logical half. But it’s much more complicated than that. Marnie Halpern studies how left-right differences arise in the developing...
The first step in gene expression is the formation of an RNA copy of its DNA. This step, called transcription, takes place in the cell nucleus. Transcription requires an enzyme called RNA polymerase to catalyze the synthesis of the RNA from the DNA template. This, in addition to other processing...
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Baltimore, MD—Studying how our bodies metabolize lipids such as fatty acids, triglycerides, and cholesterol can teach us about cardiovascular disease, diabetes, and other health problems, as well as...
Aging-related inflammation can drive the decline of a critical structural protein called lamin-B1, which contributes to diminished immune function in the thymus, according to research from Carnegie...
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