Genetics & Developmental Biology Stories
Baltimore, MD— Recently published work from Carnegie’s Allan Spradling and Wanbao Niu revealed in unprecedented detail the genetic instructions immature egg cells go through step by step...
Baltimore, MD— Recent work led by Carnegie’s Kamena Kostova revealed a new quality control system in the protein production assembly line with possible implications for understanding...
Baltimore, MD— Carnegie’s Department of Embryology welcomes two new Staff Scientists, both of whom specialize in researching the symbiotic relationships between species.
Brittany Belin...
Baltimore, MD—New work led by Carnegie’s Meredith Wilson and Steve Farber identifies a potential therapeutic target for clogged arteries and other health risks that stem from an excess of...
Baltimore, MD— New work from a team of Carnegie cell, genomic, and developmental biologists solves a longstanding marine science mystery that could aid coral conservation. The researchers...
Baltimore, MD— Carnegie’s Director of Embryology Yixian Zheng is one of 15 scientists awarded a grant from the...
Baltimore, MD—Antibiotics can make easy work of infections. But how do they affect the complex ecosystems of friendly bacteria that make up our microbiome?
“When a doctor prescribes...
Baltimore, MD— They say a picture is worth 1,000 words. But what about a real-time window into the complexity of the gastrointestinal system?
A new research tool allowed biologists to...
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The Marnie Halpern laboratory studies how left-right differences arise in the developing brain and discovers the genes that control this asymmetry. Using the tiny zebrafish, Danio rerio, they explores how regional specializations occur within the neural tube, the embryonic tissue that develops into...
The Spradling laboratory studies the biology of reproduction. By unknown means eggs reset the normally irreversible processes of differentiation and aging. The fruit fly Drosophila provides a favorable multicellular system for molecular genetic studies. The lab focuses on several aspects of egg...
The Zheng lab studies cell division including the study of stem cells, genome organization, and lineage specification. They study the mechanism of genome organization in development, homeostasis—metabolic balance-- and aging; and the influence of cell morphogenesis, or cell shape and...
In mammals, most lipids, such as fatty acids and cholesterol, are absorbed into the body via the small intestine. The complexity of the cells and fluids that inhabit this organ make it very difficult to study in a laboratory setting. The goal of the Farber lab is to better understand the cell and...
The first step in gene expression is the formation of an RNA copy of its DNA. This step, called transcription, takes place in the cell nucleus. Transcription requires an enzyme called RNA polymerase to catalyze the synthesis of the RNA from the DNA template. This, in addition to other processing...
The mouse is a traditional model organism for understanding physiological processes in humans. Chen-Ming Fan uses the mouse to study the underlying mechanisms involved in human development and genetic diseases. He concentrates on identifying and understanding the signals that direct the...
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Baltimore, MD— Eggs take a long time to produce in the ovary, and thus are one of a body’s precious resources. It has been theorized that the body has mechanisms to help the ovary ensure that...
Every high school biology class learns about the process of mitosis, the series of steps through which a cell divides itself into two daughter cells, each with the same genetic material. Mitosis...
Using the CRISPR/Cas9 genome-editing tool, biologists can now target specific genes for mutation and then see how this induced mutation manifests in an organism. But sometimes an organism compensates...
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