Genetics & Developmental Biology Stories
Carnegie’s Department of Embryology scientist Steven Farber and team have been awarded a 5-year $3.3-million NIH grant to identify novel pharmaceuticals for combating a host of diseases associated...
Tasuku Honjo, a postdoctoral fellow in the Brown Lab at the Department of Embryology 1971-1973, shares the 2018 Nobel Prize in Physiology or Medicine.
The ...
Baltimore, MD— Body organs such as the intestine and ovaries undergo structural changes in response to dietary nutrients that can have lasting impacts on metabolism, as well as cancer susceptibility...
Ethan Greenblatt, a senior postdoctoral associate in Allan Spradling’s lab at the Department of Embryology, has been awarded the eleventh Postdoctoral Innovation and Excellence Award. Greenblatt has...
Baltimore, MD—The Pew Charitable Trust has awarded Carnegie’s Steve Farber and colleague John F. Rawls of Duke University a $200,000 grant to investigate how dietary nutrients, such as fats, alter...
Baltimore, MD—New work from Carnegie’s Ethan Greenblatt and Allan Spradling reveals that the genetic factors underlying fragile X syndrome, and potentially other autism-related disorders, stem from...
Baltimore MD—Almost half of our DNA sequences are made up of jumping genes—also known as transposons. They jump around the genome in developing sperm and egg cells and are important to evolution. But...
Baltimore, MD—A tremendous amount of genetic material must be packed into the nucleus of every cell—a tiny compartment. One of the biggest challenges in biology is to understand how certain regions...
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The Gall laboratory studies all aspects of the cell nucleus, particularly the structure of chromosomes, the transcription and processing of RNA, and the role of bodies inside the cell nucleus, especially the Cajal body (CB) and the histone locus body (HLB).
Much of the work makes use of the giant...
The Spradling laboratory studies the biology of reproduction. By unknown means eggs reset the normally irreversible processes of differentiation and aging. The fruit fly Drosophila provides a favorable multicellular system for molecular genetic studies. The lab focuses on several aspects of egg...
Stem cells make headline news as potential treatments for a variety of diseases. But undertstanding the nuts and bolts of how they develop from an undifferentiated cell that gives rise to cells that are specialized such as organs, or bones, and the nervous system, is not well understood.
The...
The mouse is a traditional model organism for understanding physiological processes in humans. Chen-Ming Fan uses the mouse to study the underlying mechanisms involved in human development and genetic diseases. He concentrates on identifying and understanding the signals that direct the...
There is a lot of folklore about left-brain, right-brain differences—the right side of the brain is supposed to be the creative side, while the left is the logical half. But it’s much more complicated than that. Marnie Halpern studies how left-right differences arise in the developing brain and...
Staff associate Christoph Lepper, with colleagues, overturned previous research that identified critical genes for making muscle stem cells. It turns out that the genes that make muscle stem cells in the embryo are surprisingly not needed in adult muscle stem cells to regenerate muscles after...
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Baltimore, MD — The study of muscular system protein myostatin has been of great interest to researchers as a potential therapeutic target for people with muscular disorders. Although much is known...
Baltimore, MD—Carnegie’s BioEYES K-12 science educational program launches a new center sponsored by the University of Utah, Department of Pediatrics, Pediatric Research Enterprise. The new program...
A tremendous amount of genetic material must be packed into the nucleus of every cell—a tiny compartment. One of the biggest challenges in biology is to understand how certain regions of this highly...
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