Genetics & Developmental Biology Stories
Baltimore, MD—The interactions that take place between the species of microbes living in the gastrointestinal system often have large and unpredicted effects on health, according to new work...
Baltimore, MD—Since Carnegie Institution’s Barbara McClintock received her Nobel Prize on her discovery of jumping genes in 1983, we have learned that almost half of our DNA is made up of...
Carnegie’s Department of Embryology scientist Steven Farber and team have been awarded a 5-year $3.3-million NIH grant to identify novel pharmaceuticals for combating a host of diseases...
Tasuku Honjo, a postdoctoral fellow in the Brown Lab at the Department of Embryology 1971-1973, shares the 2018 Nobel Prize in Physiology or Medicine.
The ...
Baltimore, MD— Body organs such as the intestine and ovaries undergo structural changes in response to dietary nutrients that can have lasting impacts on metabolism, as well as cancer...
Ethan Greenblatt, a senior postdoctoral associate in Allan Spradling’s lab at the Department of Embryology, has been awarded the eleventh Postdoctoral Innovation and Excellence Award....
Baltimore, MD—The Pew Charitable Trust has awarded Carnegie’s Steve Farber and colleague John F. Rawls of Duke University a $200,000 grant to investigate how dietary nutrients, such as...
Baltimore, MD—New work from Carnegie’s Ethan Greenblatt and Allan Spradling reveals that the genetic factors underlying fragile X syndrome, and potentially other autism-related disorders...
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The Zheng lab studies cell division including the study of stem cells, genome organization, and lineage specification. They study the mechanism of genome organization in development, homeostasis—metabolic balance-- and aging; and the influence of cell morphogenesis, or cell shape and...
The Gall laboratory studies all aspects of the cell nucleus, particularly the structure of chromosomes, the transcription and processing of RNA, and the role of bodies inside the cell nucleus, especially the Cajal body (CB) and the histone locus body (HLB).
Much of the work makes use of the giant...
Stem cells make headline news as potential treatments for a variety of diseases. But undertstanding the nuts and bolts of how they develop from an undifferentiated cell that gives rise to cells that are specialized such as organs, or bones, and the nervous system, is not well understood....
In mammals, most lipids, such as fatty acids and cholesterol, are absorbed into the body via the small intestine. The complexity of the cells and fluids that inhabit this organ make it very difficult to study in a laboratory setting. The goal of the Farber lab is to better understand the cell and...
Yixian Zheng is Director of the Department of Embryology. Her lab has a long-standing interest in cell division. In recent years, their findings have broadened their research using animal models, to include the study of stem cells, genome organization, and lineage specification—how stem cells...
Junior investigator Zhao Zhang joined Carnegie in November 2014. He studies how elements with the ability to “jump” around the genome, called transposons, are controlled in egg, sperm, and other somatic tissues in order to understand how transposons contribute to genomic...
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YouTubeBaltimore, MD— As all school-children learn, cells divide using a process called mitosis, which consists of a number of phases during which duplicate copies of the cell's DNA-containing...
Every high school biology class learns about the process of mitosis, the series of steps through which a cell divides itself into two daughter cells, each with the same genetic material. Mitosis...
A tremendous amount of genetic material must be packed into the nucleus of every cell—a tiny compartment. One of the biggest challenges in biology is to understand how certain regions of this...
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