Carnegie researchers recently constructed genetically encoded FRET sensors for a variety of important molecules such as glucose and glutamate. The centerpiece of these sensors is a recognition element derived from the superfamily of bacterial binding protiens called periplasmic binding protein (...
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Carnegie is renowned for its post-doctoral and graduate student fellowship programs, which operate on each of the Carnegie campuses. Our fellows participate fully in the institution’s vigorous intellectual life, and have complete access to the laboratory instruments and facilities at the...
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The NASA Astrobiology Institute (NAI) Carnegie Team focuses on life’s chemical and physical evolution, from the interstellar medium, through planetary systems, to the emergence and detection of life by studying extrasolar planets, Solar System formation, organic rich primitive planetary bodies,...
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Together with Dr. Jamie Shuda, Steve Farber created a Science Outreach Program, Project BioEYES, that incorporates life science and laboratory education using zebrafish. The outreach program has two main components: educating teachers through hands-on training and tours of our zebrafish facility,...
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Carnegie Academy for Science Education
Scientific literacy is now recognized to be crucial for our nation's progress in the 21st century. The Carnegie Institution, a pre-eminent basic research organization, has fostered the development of scientific knowledge since the early 20th century. For many years, this meant the training of...
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Along with Alycia Weinberger and Ian Thompson, Alan Boss has been running the Carnegie Astrometric Planet Search (CAPS) program, which searches for extrasolar planets by the astrometric method, where the planet's presence is detected indirectly through the wobble of the host star around the center...
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Carnegie's Paul Butler has been leading work on a multiyear project to carry out the first reconnaissance of all 2,000 nearby Sun-like stars within 150 light-years of the solar system (1 lightyear is about 9.4 trillion kilometers). His team is currently monitoring about 1,700 stars, including 1,000...
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CALL FOR PROPOSALS Following Andrew Carnegie’s founding encouragement of liberal discovery-driven research, the Carnegie Institution for Science offers its scientists a new resource for pursuing bold ideas. Carnegie Science Venture grants are internal awards of up to $100,000 that are intended to...
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Carnegie researchers are developing new scientific approaches that integrate phylogenetic, chemical and spectral remote sensing perspectives - called Spectranomics - to map canopy function and biological diversity throughout tropical forests of the world. Mapping the composition and chemistry of...
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CDAC is a multisite, interdisciplinary center headquartered at Carnegie to advance and perfect an extensive set of high pressure and temperature techniques and facilities, to perform studies on a broad range of materials in newly accessible pressure and temperature regimes, and to integrate and...
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Monitoring tropical deforestation and forest degradation with satellites can be an everyday activity for non-experts who support environmental conservation, forest management, and resource policy development. Through extensive observation of user needs, the Greg Asner team developed CLASlite ( the...
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DC Stem Network
The DC STEM Network unites community partners to help inspire and prepare all DC youth to succeed, lead, and innovate in STEM fields and beyond. The Network connects educators, industry experts, community organizations, and colleges to support STEM learning across the city. The Network was formed...
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Carbon plays an unparalleled role in our lives: as the element of life, as the basis of most of society’s energy, as the backbone of most new materials, and as the central focus in efforts to understand Earth’s variable and uncertain climate. Yet in spite of carbon’s importance, scientists remain...
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Revolutionary progress in understanding plant biology is being driven through advances in DNA sequencing technology. Carnegie plant scientists have played a key role in the sequencing and genome annotation efforts of the model plant Arabidopsis thaliana and the soil alga Chlamydomonas reinhardtii....
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The Energy Frontier Research in Extreme Environments Center (EFree) was established to accelerate the discovery and synthesis of kinetically stabilized, energy-related materials using extreme conditions. Partners in this Carnegie-led center include world-leading groups in five universities—Caltech...
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Chris Field is a co-principal investigator of the Jasper Ridge Global Change Experiment at the Jasper Ridge Biological Preserve in northern California. The site, designed to exploit grasslands as models for understanding how ecosystems may respond to climate change, hosts a number of studies of the...
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Starting in 2005, the High Lava Plains project is focused on a better understanding of why the Pacific Northwest, specifically eastern Oregon's High Lava Plains, is so volcanically active. This region is the most volcanically active area of the continental United States and it's relatively young....
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The High Pressure Collaborative Access Team (HPCAT) was established to advance cutting-edge, multidisciplinary, high-pressure science and technology using synchrotron radiation at the Advanced Photon Source (APS) of Argonne National Laboratory in Illinois. The integrated HPCAT facility has...
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The Geophysical Laboratory has made important advances in the growth of diamond by chemical vapor deposition (CVD).  Methods have been developed to produce single-crystal diamond at low pressure having a broad range of properties.
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The thyroid gland secretes thyroxine (TH), a hormone essential for the growth and development of all vertebrates including humans. To understand TH action, the Donald Brown lab studies one of the most dramatic roles of the hormone, the control of amphibian metamorphosis—the process by which a...
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In March 2014, a technical support unit (TSU) of ten, headquartered at Global Ecology, had successfully completed a herculean management effort for the 2000-page assessment Climate Change 2014: Impacts, Adaptation, and Vulnerability, including two summaries. They were issued by the United Nations (...
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High-elevation, low relief surfaces are common on continents. These intercontinental plateaus influence river networks, climate, and the migration of plants and animals. How these plateaus form is not clear. Researchers are studying the geodynamic processes responsible for surface uplift in the...
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Carnegie scientists participate in NASA's Kepler missions, the first mission capable of finding Earth-size planets around other stars. The centuries-old quest for other worlds like our Earth has been rejuvenated by the intense excitement and popular interest surrounding the discovery of hundreds of...
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The Marnie Halpern laboratory studies how left-right differences arise in the developing brain and discovers the genes that control this asymmetry. Using the tiny zebrafish, Danio rerio, they explores how regional specializations occur within the neural tube, the embryonic tissue that develops into...
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Established in June of 2016 with a generous gift of $50,000 from Marilyn Fogel and Christopher Swarth, the Marilyn Fogel Endowed Fund for Internships will provide support for “very young budding scientists” who wish to “spend a summer getting their feet wet in research for the very first time.” ...
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Fifty years ago, Americans led the world in math and science, claiming some of the most important inventions and technological breakthroughs of the 20th century.  Today, American 15-year-olds rank 25th in math compared to their peers worldwide.  Math ƒor America DC strives to reclaim America’s...
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The Zheng lab studies cell division including the study of stem cells, genome organization, and lineage specification. They study the mechanism of genome organization in development, homeostasis—metabolic balance-- and aging; and the influence of cell morphogenesis, or cell shape and steructure, ...
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The MESSENGER (MErcury Surface, Space ENvironment, GEochemistry, and Ranging) mission to orbit Mercury following three flybys of that planet is a scientific investigation of the planet Mercury. Understanding Mercury, and the forces that have shaped it is fundamental to understanding the terrestrial...
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Until now, computer models have been the primary tool for estimating photosynthetic productivity on a global scale. They are based on estimating a measure for plant energy called gross primary production (GPP), which is the rate at which plants capture and store a unit of chemical energy as biomass...
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Coral reefs are havens for marine biodiversity and underpin the economies of many coastal communities. But they are very sensitive to changes in ocean chemistry resulting from greenhouse gas emissions, as well as to pollution, warming waters, overdevelopment, and overfishing. Reefs use a mineral...
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Andrew Steele joins the Rosetta team as a co-investigator working on the COSAC instrument aboard the Philae lander (Fred Goesmann Max Planck Institute - PI). On 12 November 2014 the Philae system will be deployed to land on the comet and begin operations. Before this, several analyses of the comet...
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Today, humanity is increasingly aware of the impact it has on the environment and the difficulties caused when the environment impacts our communities. Environmental change can be particularly harsh when the plants we use for food, fuel, feed and fiber are affected by this change. High salinity is...
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Approximately half of the gene sequences of human and mouse genomes comes from so-called mobile elements—genes that jump around the genome. Much of this DNA is no longer capable of moving, but is likely “auditioning”  perhaps as a regulator of gene function or in homologous recombination, which is...
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Superdeep diamonds are  tiny time capsules carrying unchanged impurities made eons ago and providing researchers with important clues about Earth’s formation.  Diamonds derived from below the continental lithosphere, are most likely from the transition zone (415 miles, or 670km deep) or the top of...
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The Anglo-Australian Planet Search (AAPS) is a long-term program being carried out on the 3.9-meter Anglo-Australian Telescope (AAT) to search for giant planets around more than 240 nearby Sun-like stars. The team, including Carnegie scientists,  uses the "Doppler wobble" technique to search for...
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The Spradling laboratory studies the biology of reproduction. By unknown means eggs reset the normally irreversible processes of differentiation and aging. The fruit fly Drosophila provides a favorable multicellular system for molecular genetic studies. The lab focuses on several aspects of egg...
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The Carnegie Airborne Observatory (CAO), developed by GregAsner, is a fixed-wing aircraft that sweeps laser light across the vegetation canopy to image it in brilliant 3-D. The data can determine the location and size of each tree at a resolution of 3.5 feet (1.1 meter), a level of detail that is...
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The Carnegie Hubble program is an ongoing comprehensive effort that has a goal of determining the Hubble constant, the expansion rate of the universe,  to a systematic accuracy of 2%. As part of this program, astronomers are obtaining data at the 3.6 micron wavelength using the Infrared Array...
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The recent discovery that the universe is expanding at an accelerating rate has profoundly affected physics. If the universe were gravity-dominated then it should be decelerating. These contrary results suggest a new form of “dark energy”—some kind of repulsive force—is driving the universe. To get...
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The Carnegie Irvine Galaxy Survey is obtaining high-quality optical and near-infrared images of several hundred of the brightest galaxies in the southern hemisphere sky, at Carnegie’s Las Campanas Observatory to investigate the structural properties of galaxies. For more see    http://cgs.obs....
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The Carnegie-Spitzer-IMACS (CSI) survey, currently underway at the Magellan-Baade 6.5m telescope in Chile, has been specifically designed to characterize normal galaxies and their environments at a distance of about 4 billion years post Big Bang, expresses by astronomers as  z=1.5. The survey...
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Carbon plays an unparalleled role in our lives: as the element of life, as the basis of most of society’s energy, as the backbone of most new materials, and as the central focus in efforts to understand Earth’s variable and uncertain climate. Yet in spite of carbon’s importance, scientists remain...
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The Earthbound Planet Search Program has discovered hundreds of planets orbiting nearby stars using telescopes at Lick Observatory, Keck Observatory, the Anglo-Australian Observatory, Carnegie's Las Campanas Observatory, and the ESO Paranal Observatory.  Our multi-national team has been collecting...
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Carnegie will receive Phase II funding through Grand Challenges Explorations, an initiative created by the Bill & Melinda Gates Foundation that enables individuals worldwide to test bold ideas to address persistent health and development challenges. Department of Plant Biology Director Wolf...
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The Giant Magellan Telescope will be one member of the next class of super giant earth-based telescopes that promises to revolutionize our view and understanding of the universe. It will be constructed in the Las Campanas Observatory in Chile. Commissioning of the telescope is scheduled to begin in...
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Stem cells make headline news as potential treatments for a variety of diseases. But undertstanding the nuts and bolts of how they develop from an undifferentiated cell  that gives rise to cells that are specialized such as organs, or bones, and the nervous system, is not well understood.  The...
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The Gall laboratory studies all aspects of the cell nucleus, particularly the structure of chromosomes, the transcription and processing of RNA, and the role of bodies inside the cell nucleus, especially the Cajal body (CB) and the histone locus body (HLB). Much of the work makes use of the giant...
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Fresh water constitutes less than 1% of the surface water on earth, yet the importance of this simple molecule to all life forms is immeasurable. Water represents the most vital reagent for chemical reactions occurring in a cell. In plants, water provides the structural support necessary for plant...
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The Fan laboratory studies the molecular mechanisms that govern mammalian development, using the mouse as a model. They use a combination of biochemical, molecular and genetic approaches to identify and characterize signaling molecules and pathways that control the development and maintenance of...
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The fund supports a postdoctoral fellowship in astronomy that rotates between the Carnegie Science departments of Terrestrial Magnetism in Washington, D.C., and the Observatories in Pasadena California. 
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In mammals, most lipids, such as fatty acids and cholesterol, are absorbed into the body via the small intestine. The complexity of the cells and fluids that inhabit this organ make it very difficult to study in a laboratory setting. The goal of the Farber lab is to better understand the cell and...
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Anna Michalak’s team combined sampling and satellite-based observations of Lake Erie with computer simulations and determined that the 2011 record-breaking algal bloom in the lake was triggered by long-term agricultural practices coupled with extreme precipitation, followed by weak lake circulation...
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The WGESP was charged with acting as a focal point for research on extrasolar planets and organizing IAU activities in the field, including reviewing techniques and maintaining a list of identified planets. The WGESP developed a Working List of extrasolar planet candidates, subject to revision. In...
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